Results 51 to 60 of about 2,480 (127)
Journal of Nanobiotechnology, 2023 Hepatocellular carcinoma (HCC) is a leading cause of death globally. Even though the progressive invention of some very potent therapeutics has been seen, the success is limited due to the chemotherapeutic resistance and recurrence in HCC.
Moumita Dhara +6 more
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ChemMedChem, Volume 21, Issue 9, 14 May 2026.From modular COF design to biomedical translation, this Review maps how linkage chemistry, topology, pore environment, and particle engineering govern bioperformance, therapeutic and diagnostic function, safety, and clinical readiness. Covalent organic frameworks (COFs) are a versatile class of crystalline porous materials with growing potential in ...
Julia Kolodziejczyk +1 more
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Small Science, Volume 6, Issue 5, May 2026.Aptamer‐functionalized nanocarriers represent a versatile platform for targeted therapy in bone and joint diseases. This review presents five complementary design strategies: free aptamers for soluble targets, bispecific multivalent constructs for enhanced avidity, nanoparticle‐conjugated aptamers for selective tissue accumulation, aptamer‐based ...
Hamdi Al‐Azzani +5 more
wiley +1 more source
Recent Advances in Tetrahedral Framework Nucleic Acids for Multimodal Synergistic Cancer Therapy
Aggregate, Volume 7, Issue 4, April 2026.This review summarizes recent advances in tFNA‐based multimodal cancer therapy, including structural features, delivery strategies, and therapeutic regimens addressing key challenges in cancer treatment. We outline design principles, address translational hurdles, and highlight intelligent response and immune regulation as promising directions to ...
Zishan Huang +7 more
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Advanced Functional Materials, Volume 36, Issue 25, 26 March 2026.Fluorescent nanodiamonds (fNDs) have emerged as an invaluable quantum sensing platform for biological and biochemical systems. This paper investigates the influence of common surface functionalization strategies for bioconjugation on the quantum properties of nitrogen vacancy (NV) centers in nanodiamonds.
Anja Sadžak +6 more
wiley +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
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Small Structures, Volume 7, Issue 3, March 2026.Multidrug resistance in breast cancer constitutes a major therapeutic obstacle. This review examines light‐activated nanoplatforms combining photothermal and photodynamic therapies to overcome this challenge. Through rational design, these systems enable spatiotemporal control, enhanced tumor targeting, and synergistic antitumor efficacy.
Xianghui Duan +9 more
wiley +1 more source
International Journal of Nanomedicine, 2019 Jing Zhao,1 Peidang Liu,1,2 Jun Ma,3 Dongdong Li,1 Huiquan Yang,1 Wenbin Chen,1 Yaowen Jiang2 1School of Medicine, Southeast University, Nanjing 210009, People’s Republic of China; 2Jiangsu Key Laboratory for Biomaterials and Devices, Southeast ...
Zhao J +6 more
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General cell-binding activity of intramolecular G-quadruplexes with parallel structure.
PLoS ONE, 2013 G-quadruplexes (G4s) are four-stranded nucleic acid structures adopted by some repetitive guanine-rich sequences. Putative G-quadruplex-forming sequences (PQSs) are highly prevalent in human genome.
Tianjun Chang +7 more
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International Journal of Nanomedicine, 2022 Zhengyue Kang,1,2,* Min Yang,1,2,* Xiaoling Feng,1,2 Hongjian Liao,1,2 Zhifei Zhang,1,2 Yonghong Du1,2 1State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing ...
Kang Z +5 more
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