Results 61 to 70 of about 150,558 (259)

Development of a Genome-Edited Tomato With High Ascorbate Content During Later Stage of Fruit Ripening Through Mutation of SlAPX4

Frontiers in Plant Science, 2022
Ascorbate is an essential antioxidant substance for humans. Due to the lack of ascorbate biosynthetic enzyme, a human must intake ascorbate from the food source.
Ju Hui Do, Seo Young Park, Se Hee Park, Hyun Min Kim, Sang Hoon Ma, Thanh Dat Mai, Jae Sung Shim, Young Hee Joung   +7 more
doaj   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

High Throughput Analyses of Ascorbate-turnover Enzyme Activities in Rice (Oryza sativa L.) Seedlings

Bio-Protocol, 2021
Ascorbate (Vitamin C) fulfills various functions in plant photosynthesis and abiotic stress tolerance. The four key enzymes involved in the ascorbate-turnover pathway are ascorbate peroxidase, ascorbate oxidase, monodehydroascorbate reductase, and ...
Lin Wu, Yanru Feng, Frederike Zeibig, Muhammad Shahedul Alam, Michael Frei   +4 more
doaj   +1 more source

Ascorbate and peroxidase changes during pregnancy in albino rat and Swiss mouse.

, 1979
From the 1st to 6th days of pregnancy in the rat, while the blastocyst is still in the fallopian tube, there is high peroxidase activity in the corpus luteum, the blastocyst, and there is high peroxidase activity in the endometrium. On day 8 of pregnancy,
P Agrawal, M M Laloraya
core   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Drought induced programmed cell death and associated changes in antioxidants, proteases, and lipid peroxidation in wheat leaves

Biologia Plantarum, 2013
Two wheat (Triticum aestivum L.) genotypes with varying degree of drought tolerance were used to analyze programmed cell death (PCD) and related biochemical changes under drought stress.
A. Hameed, M. Goher, N. Iqbal
doaj   +1 more source

The TL29 Protein is Lumen Located, Associated with PSII and Not an Ascorbate Peroxidase

, 2009
The TL29 protein is one of the more abundant proteins in the thylakoid lumen of plant chloroplasts. Based on its sequence homology to ascorbate peroxidases, but without any supporting biochemical evidence, TL29 was suggested to be involved in the plant ...
Granlund, Irene,, Granlund, Irene, Schubert, Maria,, Schröder, Wolfgang P,, Funk, Christiane, Storm, Patrik, Garcia-Cerdan, Jose G., Storm, Patrik,, Funk, Christiane,, Schröder, Wolfgang P., García-Cerdán, José G,   +10 more
core   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Comparison of two peroxidases with high potential for biotechnology applications – HRP vs. APEX2

Computational and Structural Biotechnology Journal
Peroxidases are essential elements in many biotechnological applications. An especially interesting concept involves split enzymes, where the enzyme is separated into two smaller and inactive proteins that can dimerize into a fully active enzyme.
Sanja Škulj, Matej Kožić, Antun Barišić, Aitor Vega, Xevi Biarnés, Ivo Piantanida, Ivan Barisic, Branimir Bertoša   +7 more
doaj   +1 more source

Nitric Oxide Inhibition of Tobacco Catalase and Ascorbate Peroxidase

Molecular Plant-Microbe Interactions, 2000
We used a variety of nitric oxide (NO) donors to demonstrate that NO inhibits the activities of tobacco catalase and ascorbate peroxidase (APX). This inhibition appears to be reversible because removal of the NO donor led to a significant recovery of ...
Daniel Clark, Jörg Durner, Duroy A. Navarre, Daniel F. Klessig   +3 more
doaj   +1 more source