Results 91 to 100 of about 1,823 (155)

ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning.

International journal of physiology, pathophysiology and pharmacology, 2011
Acid-sensing ion channels, ASICs, are proton-gated cation channels widely expressed in peripheral sensory neurons and in neurons of the central nervous system that play an important role in a variety of physiological and pathological processes. To further confirm the role played by ASIC1a in cerebral ischemia, here we examined the involvement of this ...
PIGNATARO, GIUSEPPE, CUOMO, ORNELLA, ESPOSITO, ELGA, SIRABELLA, ROSSANA, DI RENZO, GIANFRANCO MARIA LUIGI, ANNUNZIATO, LUCIO   +5 more
openaire   +2 more sources

A Selectivity Filter at the Lower End of ASIC1a [PDF]

Biophysical Journal, 2017
Timothy Lynagh, Emelie Flood, Celine Boiteux, Matthias Wulf, Janne M. Colding, Vitaly V. Komnatnyy, Toby W. Allen, Stephan A. Pless   +7 more
openaire   +1 more source

Inhibitor-Induced Conformational Changes in ASIC1A [PDF]

Biophysical Journal, 2018
Lund, Camilla, Borg, Christian B., Lynagh, Timothy, Pless, Stephan A.   +3 more
openaire   +2 more sources

Mitochondrial acid-sensing ion channel 1a deficiency induces mitochondrial dysfunction in pulmonary arterial smooth muscle cells. [PDF]

Am J Physiol Lung Cell Mol Physiol
Tuineau MN, Herbert LM, Medina HE, Naik JS, Resta TC, Jernigan NL.   +5 more
europepmc   +1 more source

Acid-sensing ion channels and their role in controlling pain in the post-operative stage. [PDF]

Int J Physiol Pathophysiol Pharmacol
Warikoo G, Sun A, Chu XP.
europepmc   +1 more source

Acetazolamide inhibition of carbonic anhydrase 4 reverses opioid-induced synaptic rearrangements in nucleus accumbens and reduces drug-seeking behavior. [PDF]

Neuropsychopharmacology
Gupta SC, Taugher-Hebl RJ, Ghobbeh A, Jahnke MT, Fan R, LaLumiere RT, Wemmie JA.   +6 more
europepmc   +1 more source

Molecular mechanisms and hotspots of pH sensing in ASIC1a revealed by computational and functional analysis. [PDF]

Commun Biol
Bignucolo O, Molton O, Gautschi I, Kellenberger S.   +3 more
europepmc   +1 more source

Human acid-sensing ion channel 1a/3 heteromers at a 1:2 ratio expand the functional capabilities of homomeric ASIC3 and are likely to be physiologically relevant. [PDF]

Natl Sci Rev
Osmakov DI, Dubodel ES, Kalinovskii AP, Koshelev SG, Andreev YA, Korolkova YV, Kozlov SA.   +6 more
europepmc   +1 more source

Identification, characterization, and structure-activity relationship of the ASIC3-selective peptide WRPRFa. [PDF]

Commun Chem
Chien C, Yang ND, Jiang V, Amagasu SM, Gilchrist JM.   +4 more
europepmc   +1 more source

ASIC1a Induces Excessive Mitophagy and PANoptosis of Chondrocyte by the Inhibition of SIRT3 Mitochondrial Translocation. [PDF]

Theranostics
Zai Z, Qian X, Xu Y, Lv H, Hao M, Tao Y, Rui L, Zhang X, Peng X, Zhang Y, Chen F.   +10 more
europepmc   +1 more source