Results 71 to 80 of about 5,490,229 (291)
The design and application of associative memories for scene analysis [PDF]
, 1986 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis investigates a novel scene analysis system that determines the identity and the relative positions of unconstrained objects within a natural ...
Austin, James
core +6 more sources
Effects of psychological stress on innate immunity and metabolism in humans: a systematic analysis. [PDF]
PLoS ONE, 2012 Stress is perhaps easiest to conceptualize as a process which allows an organism to accommodate for the demands of its environment such that it can adapt to the prevailing set of conditions.
Sushri Priyadarshini, Palok Aich
doaj +1 more source
Analyzing a co-occurrence gene-interaction network to identify disease-gene association [PDF]
BMC Bioinformatics, 2019 Understanding the genetic networks and their role in chronic diseases (e.g., cancer) is one of the important objectives of biological researchers. In this work, we present a text mining system that constructs a gene-gene-interaction network for the entire human genome and then performs network analysis to identify disease-related genes.
Amira Al-Aamri +4 more
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Identification of a gene regulatory network associated with prion replication
The EMBO Journal, 2014 Abstract Prions consist of aggregates of abnormal conformers of the cellular prion protein (PrP C ). They propagate by recruiting host‐encoded PrP C although the critical interacting proteins and the reasons for the differences in ...
Marbiah, Masue M +13 more
openaire +4 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Age-related associative deficits are absent with nonwords [PDF]
, 2011 Words and nonwords were used as stimuli to assess item and associative recognition memory performance in young and older adults. Participants were presented with pairs of items and then tested on both item memory (old/new items) and associative memory ...
Elizabeth A. Maylor +3 more
core +1 more source
, 2022 This code accompanies the manuscript "Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root"
Hsu-Che-Wei +2 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source