Results 1 to 10 of about 1,135 (159)
Molecules, 2021 Radix Astragali is referred to as a variety of food-medicine herb, and it is commonly applied as Traditional Chinese Medicine (TCM). However, it is extremely difficult to extract its bio-active compounds (astragaloside IV) and apply it in food processing
Lin Xu, Lianfu Zhang, Xu Lin
exaly +4 more sources
Frontiers in Physiology, 2018 Objective: This study aims to investigate the effect of astragaloside IV on adipose lipolysis and hepatic gluconeogenesis.Methods: High-fat diet (HFD) feeding induced adipose dysfunction with enhanced endogenous glucose production in mice. The effects of
Qun Du, Aiyun Li, Imran Shair Mohammad
exaly +4 more sources
Astragaloside IV protects RGC-5 cells against oxidative stress
Neural Regeneration Research, 2018 Astragaloside IV is the main active compound of Astragalus membranaceus. Astragaloside IV has strong anti-oxidative activities and protective effects against progression of peripheral neuropathy.
Ming Hao +4 more
doaj +2 more sources
Pharmacokinetic study on the co-administration of abemaciclib and astragaloside IV in rats
Pharmaceutical Biology, 2022 Context The co-administration of abemaciclib and astragaloside IV might occur in the treatment of breast cancer.Objective This study evaluates the interaction between abemaciclib and astragaloside IV in rats and describes the potential mechanism ...
Sen Sun, Lu Liu, Hongming Song, Hong Li
doaj +3 more sources
Network Pharmacology-Based Investigation on the Anti-Osteoporosis Mechanism of Astragaloside IV
Natural Product Communications, 2021 Astragaloside IV is the main active ingredient of Astragalus membranaceus . Studies have found that it can promote the proliferation of osteoblasts and can antagonize the apoptosis of mouse osteoblasts induced by hydrogen peroxide, but its molecular ...
Li Ou +6 more
doaj +1 more source
Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway
European Journal of Histochemistry, 2021 The therapeutic effects and potential mechanisms of astragaloside IV on a rabbits dry eye model induced by benzalkonium chloride (BAC) was examined. In our study, a BAC-induced dry eye rabbit model was treated with eye drops containing astragaloside IV ...
Li Chu +3 more
doaj +1 more source
Biotechnological approaches for sustainable production of astragaloside I, II and IV from endemic species of Astracantha aitosensis (Ivan.) and Astragalus membranaceus (fisch.) by in vitro cultures [PDF]
Pharmacia, 2023 This study investigates the bioproduction of astragalosides I, II and IV from endemic Astracantha aitosensis (arnacantha) and Astragalus membranaceus species, and the biotechnological methods for increased efficiency.
Preslav Enchev +2 more
doaj +3 more sources
Brazilian Journal of Medical and Biological Research, 2023 Astragaloside IV is a biologically active substance derived from the traditional Chinese medicine Astragalus mambranaceus Bunge, and has antioxidant, anti-inflammatory, and anti-apoptotic properties.
Lei Li +8 more
doaj +1 more source
Effects of puerarin on the pharmacokinetics of astragaloside IV in rats and its potential mechanism
Pharmaceutical Biology, 2020 Context Puerarin and astragaloside IV (AS-IV) are sometimes used together for the treatment of disease in Chinese clinics, however, the drug–drug interaction between puerarin and AS-IV is still unknown.
Huan Zhang +4 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Objective: To investigate the dominant metabolic enzymes of six effective components (astragaloside IV, glycyrrhizic acid, calycosin-glucuronide, formononetin, ononin, calycosin-7-O-β-D- glucoside) of Huangqi Liuyi decoction extract (HQD).Methods: Mouse ...
Qun Wang +10 more
doaj +1 more source