Results 21 to 30 of about 1,135 (159)
Molecules, 2014 Astragaloside IV is a compound isolated from the Traditional Chinese Medicine Astragalus membranaceus, that has been reported to have bioactivities against cardiovascular disease and kidney disease.
Xu-Dong Cheng, Ming-Gang Wei
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Botanical StudiesBackground Astragaloside IV is a main medicinal active ingredient in Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao, which is also the key biomarker of A. membranaceus quality.
Haonan Wu +5 more
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Scientific Reports, 2017 In heart failure (HF), energy metabolism pathway in cardiac muscle changes from fatty acid β-oxidation to glycolysis. However, the exact mechanism is unknown.
Zhiwei Dong +9 more
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Astragaloside IV Improves Metabolic Syndrome and Endothelium Dysfunction in Fructose-Fed Rats
Molecules, 2011 The prevalence of metabolic syndrome has increased in modern society and the condition is proving to be a common precursor of cardiovascular disease. The aim of the present study was to investigate whether astragaloside IV, a major active constituent of ...
Feng Zhao +3 more
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Molecules, 2019 Background: Ischemia/reperfusion (I/R) caused by ischemic stroke treatments leads to brain injury, and autophagy plays a role in the pathology. Astragaloside IV is a potential neuroprotectant, but its underlying mechanism on cerebral I/R injury needs to ...
Yi Zhang +6 more
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Drug Design, Development and Therapy, 2018 Na Du, Zhiping Xu, Mingyue Gao, Peng Liu, Bo Sun, Xia Cao Department of Pharmacology, Jilin University, Jilin, Changchun, China Introduction: Anti-oxidative stress and inhibition of TGF-β1/Smads signaling cascade are essential therapeutic ...
Du N, Xu Z, Gao M, Liu P, Sun B, Cao X
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Scientific ReportsAstragaloside IV, a prime active component of Astragalus membranaceus, has potential as a neuroprotectant. We aimed to identify the active ingredients in A.
Juan Chen +7 more
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Astragaloside IV, as a potential anticancer agent
Frontiers in Pharmacology, 2023 Cancer is a global intractable disease, and its morbidity and mortality are increasing year by year in developing countries. Surgery and chemotherapy are often used to treat cancer, but they result in unsatisfactory outcomes, such as severe side effects and drug resistance.
Dongqin Xia +3 more
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Evaluation of astragaloside IV in hepatic fibrosis
Medicine, 2021 Abstract To evaluate the effect of astragaloside IV for hepatic fibrosis. The multiple databases like Pubmed, Embase, Cochrane databases, and China National Knowledge database were used to search for the relevant studies, and full-text articles involved in the evaluation on effect of astragaloside IV for hepatic ...
Zhongying Han, Junfeng Zhu, Zheng Han
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Anticancer effects and mechanisms of astragaloside‑IV (Review)
Oncology Reports, 2022 Astragalus membranaceus Bunge is widely used in Traditional Chinese Medicine to treat various cancers. Astragaloside‑IV (AS‑IV) is one of the major compounds isolated from A. membranaceus Bunge and has been demonstrated to have antitumor effects by inhibiting cell proliferation, invasion and metastasis in various cancer types.
Liangxing, Zhou +10 more
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