Results 31 to 40 of about 194,703 (370)
Astrocyte development—More questions than answers
Frontiers in Cell and Developmental Biology, 2023 The past 15–20 years has seen a remarkable shift in our understanding of astrocyte contributions to central nervous system (CNS) function. Astrocytes have emerged from the shadows of neuroscience and are now recognized as key elements in a broad array of
Kathryn M. Markey +6 more
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Mechanosensory Signaling in Astrocytes [PDF]
The Journal of Neuroscience, 2020 Mechanosensitivity is a well-known feature of astrocytes, however, its underlying mechanisms and functional significance remain unclear. There is evidence that astrocytes are acutely sensitive to decreases in cerebral perfusion pressure and may function as intracranial baroreceptors, tuned to monitor brain blood flow.
Alexander V. Gourine +13 more
openaire +7 more sources
The Neurotropic Parasite Toxoplasma gondii Induces Astrocyte Polarization Through NFκB Pathway
Frontiers in Medicine, 2019 Background:Toxoplasma gondii is a protozoan parasite that chronically infects nearly one-third of the world's human population. In immunosuppressed individuals and fetus, infection with T.
Yu Jin +6 more
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Astrocyte polarization in glaucoma: a new opportunity
Neural Regeneration Research, 2022 Astrocyte polarization is a new concept which is similar to microglia polarization and in which astrocytes are classified as A1 (neurotoxic) and A2 (neuroprotective).
Yi-Xin Liu, Hao Sun, Wen-Yi Guo
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Controlling the spontaneous firing behavior of a neuron with astrocyte [PDF]
, 2022 Mounting evidence in recent years suggests that astrocytes, a sub-type of glial cells, not only serve metabolic and structural support for neurons and synapses but also play critical roles in regulation of proper functioning of the nervous system.
arxiv +1 more source
Normal aging induces A1-like astrocyte reactivity
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance In aging, the brain becomes vulnerable to injury and cognitive function declines, but the mechanisms responsible are unknown. Astrocytes, the most abundant class of glial cells, are vital for the proper function of the central nervous system,
L. Clarke +5 more
semanticscholar +1 more source
Parkinson's Disease, 2012 Dementia is a common feature in Parkinson’s disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes.
Simone A. van den Berge +3 more
doaj +1 more source
Nature Communications, 2023 Astrocytes contribute to brain inflammation in neurological disorders but the molecular mechanisms controlling astrocyte reactivity and their relationship to neuroinflammatory endpoints are complex and poorly understood.
Michaela M. Novakovic +7 more
doaj +1 more source
The FASEB Journal, 2010 The amygdala is connected to numerous brain regions and is involved in complex behaviors such as survival and reproduction. This highly conserved brain region is sexually dimorphic in several species with the most dramatic differences found in the medial subregion.
Cynthia L. Jordan +2 more
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Gatekeeping astrocyte identity [PDF]
eLife, 2022 New findings cast doubt on whether suppressing the RNA-binding protein PTBP1 can force astrocytes to become dopaminergic neurons.
Alexis Cooper, Benedikt Berninger
openaire +4 more sources