Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]
, 2016 Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E. +5 more
core +1 more source
Novel cell separation method for molecular analysis of neuron-astrocyte cocultures
Frontiers in Cellular Neuroscience, 2014 Over the last decade, the importance of astrocyte-neuron communication in neuronal development and synaptic plasticity has become increasingly clear. Since neuron-astrocyte interactions represent highly dynamic and reciprocal processes, we hypothesized ...
Andrea eGoudriaan +8 more
doaj +1 more source
An efficient platform for astrocyte differentiation from human induced pluripotent stem cells [PDF]
, 2017 Summary: Growing evidence implicates the importance of glia, particularly astrocytes, in neurological and psychiatric diseases. Here, we describe a rapid and robust method for the differentiation of highly pure populations of replicative astrocytes from ...
Abdelaal, Rawan +13 more
core +3 more sources
Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model
Nature Communications, 2020 Reactive astrocytes have been implicated in the pathogenesis of neurodegenerative diseases, including a non-cell autonomous effect on motor neuron survival in ALS.
Kevin A. Guttenplan +6 more
semanticscholar +1 more source
Functional immune cell–astrocyte interactions
Journal of Experimental Medicine, 2021 Astrocytes are glial cells of the central nervous system (CNS) that are strategically positioned to control CNS immunity in the context of health and disease.
L. Sanmarco +3 more
semanticscholar +1 more source
Effects of 660-nm LED photobiomodulation on drebrin expression pattern and astrocyte migration
Scientific Reports, 2023 Photobiomodulation (PBM) is a therapeutic tool that uses red or near-infrared light in medical applications. It’s applications in both central (CNS) and peripheral nervous system (PNS) are widely studied.
Sung Ryeong Yoon +3 more
doaj +1 more source
Tet1 Regulates Astrocyte Development and Cognition of Mice Through Modulating GluA1
Frontiers in Cell and Developmental Biology, 2021 Tet (Ten eleven translocation) family proteins-mediated 5-hydroxymethylcytosine (5hmC) is highly enriched in the neuronal system, and is involved in diverse biological processes and diseases.
Weize Xu +22 more
doaj +1 more source
Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation. [PDF]
, 2013 Potassium (K(+)) ions released into brain extracellular space (ECS) during neuroexcitation are efficiently taken up by astrocytes. Deletion of astrocyte water channel aquaporin-4 (AQP4) in mice alters neuroexcitation by reducing ECS [K(+)] accumulation ...
Binder, Devin K +3 more
core +2 more sources
The Emerging Nature of Astrocyte Diversity.
Annual Review of Neuroscience, 2019 Astrocytes are morphologically complex, ubiquitous cells that are viewed as a homogeneous population tiling the entire central nervous system (CNS). However, this view has been challenged in the last few years with the availability of RNA sequencing ...
B. Khakh, B. Deneen
semanticscholar +1 more source
Non-aggregated Aβ25-35 Upregulates Primary Astrocyte Proliferation In Vitro
Frontiers in Cellular Neuroscience, 2017 Amyloid beta (Aβ) is a peptide cleaved from amyloid precursor protein that contributes to the formation of senile plaques in Alzheimer’s disease (AD). The relationship between Aβ and astrocyte proliferation in AD remains controversial.
Elise C. Ohki +5 more
doaj +1 more source