Results 221 to 230 of about 31,071 (248)
Some of the next articles are maybe not open access.
Glutamate‐induced calcium signaling in astrocytes
Glia, 1994AbstractAstrocytes respond to the excitatory neurotransmitter glutamate with dynamic spatio‐temporal changes in intracellular calcium [Ca2+]i. Although they share a common wave‐like appearance, the different [Ca2+]i changes‐‐an initial spike, sustained elevation, oscillatory intracellular waves, and regenerative intercellular waves‐‐are actually ...
W T, Kim, M G, Rioult, A H, Cornell-Bell
openaire +2 more sources
Synaptic regulation of the astrocyte calcium signal
Journal of Neural Transmission, 2004During the last years, a great amount of evidence demonstrates the existence of bidirectional communication between astrocytes and neurons, which has revealed an important active role of astrocytes in the physiology of the nervous system. As a consequence of this evidence, a new concept of the synaptic physiology--"the tripartite synapse"--has been ...
Perea, Gertrudis, Araque, Alfonso
openaire +3 more sources
Calcium signalling in astrocytes and modulation of neural activity
Biosystems, 2007Starting from the experimental data on ATP evoked calcium responses in astrocytes, a biophysical model describing these phenomena was built. The simulations showed, in agreement with the experimental findings, that the intracellular calcium fluxes mediated by the P2X and P2Y purinoreceptors are responsible for the biphasic ATP evoked calcium response ...
Di Garbo A +4 more
openaire +2 more sources
IP3R1-dependent astrocyte calcium signaling in chronic itch
Neuroscience Research, 2023Astrocytes, the most abundant type of glial cell, are electrically non-excitable cells that use intracellular calcium (Ca2+) for functional regulation. Changes in intracellular Ca2+ concentration play important roles in the central nervous system (CNS), as they are involved in the release of gliotransmitters and the control of extracellular ion ...
Miho, Shiratori-Hayashi, Makoto, Tsuda
openaire +2 more sources
Optimizing Measures of Information Encoding in Astrocytic Calcium Signals
2022While most models of brain information encoding focus on neurons, recent studies have shown that calcium dynamics of astrocytes, the major class of non-neural cells in the brain, can add information about key cognitive variables that is not found in the activity of nearby neurons. This raises the question of what could be the contribution of astrocytes
Jacopo Bonato +3 more
openaire +2 more sources
Glucocorticoids?potent modulators of astrocytic calcium signaling
Glia, 1999Glucocorticoids are the first line of choice in the treatment of cerebral edema associated with brain tumors. High-dose glucocorticoids reduce the extent of edema within hours, often relieving critical increases in intracranial pressure, but the mechanisms by which glucocorticoids modulate brain water content are not well-understood.
M, Simard +7 more
openaire +2 more sources
Calcium signals in astrocytes of the fly brain promote sleep
Cell Calcium, 2021Astrocytes are morphologically and functionally linked to neuronal synapses, and can regulate the activity of neural circuits, brain function, and behavior. However, the molecular mechanisms by which astrocytes regulate fundamental biological processes such as sleep are not completely understood.
openaire +2 more sources