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Components of Astrocytic Intercellular Calcium Signaling

Molecular Neurobiology, 2000
It has become evident that astrocytes play major roles in central nervous system (CNS) function. Because they are endowed with ion channels, transport pathways, and enzymatic intermediates optimized for ionic uptake, degradation of metabolic products, and inactivation of numerous substances, they are able to sense and correct for changes in neural ...
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Calcium ion signaling in astrocytes

2008
Ca 2+ signaling has been recognized as one of the major second messenger steps in most cell types, including astrocytes, the major macroglial cell type in vertebrate nervous systems. Astrocytes are by no means a homogeneous group of glial cells, but comprise a number of different cell types (see Chap. 1).
Joachim W. Deitmer   +2 more
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Meningeal cells can communicate with astrocytes by calcium signaling

Annals of Neurology, 2000
Mechanical stimulation of adult human and rat pia-arachnoid cell cultures (loaded with calcium indicator dye) produced an increase in calcium in the stimulated cell. This change then propagated rapidly among neighboring cells, producing a calcium wave with a maximum distance of propagation and velocity resembling calcium waves in astrocytes.
B, Grafstein   +4 more
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Calcium Channel Signaling in Astrocytes

1993
It has been known for more than a century that the brain contains not only neurons but also non-neuronal cells. Most of the non-neuronal cells belong to the two glial cell types, oligodendrocytes and astrocytes. In many species, including man, they vastly outnumber neurons (1).
Leif Hertz, William E. Code
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Characteristics of thrombin-induced calcium signals in rat astrocytes

Glia, 1997
The protease thrombin seems to play a central role in events following neural injury, whereby the enzyme can act, in concert with other molecules as a hormone or as a growth factor. In cells derived from the nervous system, thrombin induces changes in morphology and proliferation. The signalling mechanisms involved in these thrombin-activated processes
J J, Ubl, G, Reiser
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Astrocyte-endothelial cell calcium signals conveyed by two signalling pathways

European Journal of Neuroscience, 2001
Astrocytes and endothelial cells are in close contact with each other at the blood-brain barrier, where important molecular transports take place. Despite these key morphological and functional properties, little is known regarding the dynamic signalling processes that occur between these two cell types.
Braet, K.   +4 more
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Aspects of Astrocytic Calcium Signaling

2006
Astrocytes constitute the largest glial cell population within the mammalian brain. A major part of astrocytic intra- and intercellular signaling occurs through dynamic changes in the cytosolic Ca2+ concentration. For a better insight into astrocytic reactions to changes in their environment, the specifics of this cellular Ca2+ code need to be ...
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The Effect of Midazolam on Calcium Signaling in Astrocytes

Annals of the New York Academy of Sciences, 1991
W E, Code, H S, White, L, Hertz
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Astrocyte: Calcium Signaling

2009
J.W. Deitmer, A. Araque
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Astrocyte Calcium Signaling

2016
Jacqueline A. Hubbard, Devin K. Binder
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