Results 1 to 10 of about 123,114 (319)

Metabolic Heterogeneity of Cerebral Cortical and Cerebellar Astrocytes

Life, 2023
Astrocytes play critical roles in regulating neuronal synaptogenesis, maintaining blood–brain barrier integrity, and recycling neurotransmitters. Increasing numbers of studies have suggested astrocyte heterogeneity in morphology, gene profile, and ...
Yuanhong Sun, Ali Winters, Linshu Wang, Kiran Chaudhari, Raymond Berry, Christina Tang, Ran Liu, Shaohua Yang   +7 more
doaj   +1 more source

Isolation of ferret astrocytes reveals their morphological, transcriptional, and functional differences from mouse astrocytes

Frontiers in Cellular Neuroscience, 2022
Astrocytes play key roles in supporting the central nervous system structure, regulating synaptic functions, and maintaining brain homeostasis. The number of astrocytes in the cerebrum has markedly increased through evolution.
Jureepon Roboon, Tsuyoshi Hattori, Dinh Thi Nguyen, Hiroshi Ishii, Mika Takarada-Iemata, Takayuki Kannon, Kazuyoshi Hosomichi, Takashi Maejima, Kengo Saito, Yohei Shinmyo, Michihiro Mieda, Atsushi Tajima, Hiroshi Kawasaki, Osamu Hori   +13 more
doaj   +1 more source

The origins and dynamic changes of C3- and S100A10-positive reactive astrocytes after spinal cord injury

Frontiers in Cellular Neuroscience, 2023
Accaumulating studies focus on the effects of C3-positive A1-like phenotypes and S100A10-positive A2-like phenotypes of reactive astrocytes on spinal cord injury (SCI), however the origins and dynamic changes of C3- and S100A10-positive reactive ...
Qing Zhao, Qing Zhao, Yi-long Ren, Yi-long Ren, Yan-jing Zhu, Rui-qi Huang, Rong-rong Zhu, Li-ming Cheng, Li-ming Cheng, Li-ming Cheng, Ning Xie, Ning Xie   +11 more
doaj   +1 more source

D1- and D2-type dopamine receptors are immunolocalized in pial and layer I astrocytes in the rat cerebral cortex

Frontiers in Neuroanatomy, 2023
Pial astrocytes, a cellular component of the cerebral cortex surface structure, are observed in a wide range of mammalian species. Despite being recognized as such, the functional potential of pial astrocytes has long been overlooked.
Satoko Oda, Hiromasa Funato, Hiromasa Funato   +2 more
doaj   +1 more source

Differential Proliferation and Maturation of Subcortical Astrocytes During Postnatal Development

Frontiers in Neuroscience, 2020
Astrocytes exhibit a region-dependent molecular and functional heterogeneity in the CNS. Although cortical astrocytes proliferate robustly during the first postnatal week and become proliferation quiescent, the temporal proliferation dynamics of ...
Temitope Shoneye, Alessandra Tamashiro Orrego, Rachel Jarvis, Yuqin Men, Ming Sum R. Chiang, Yongjie Yang, Yongjie Yang   +6 more
doaj   +1 more source

Activation of a neural stem cell transcriptional program in parenchymal astrocytes

eLife, 2020
Adult neural stem cells, located in discrete brain regions, generate new neurons throughout life. These stem cells are specialized astrocytes, but astrocytes in other brain regions do not generate neurons under physiological conditions.
Jens P Magnusson, Margherita Zamboni, Giuseppe Santopolo, Jeff E Mold, Mauricio Barrientos-Somarribas, Carlos Talavera-Lopez, Björn Andersson, Jonas Frisén   +7 more
doaj   +1 more source

Dynamic image recognition in a spiking neuron network supplied by astrocytes [PDF]

, 2022
Mathematical model of spiking neuron network (SNN) supplied by astrocytes is investigated. The astrocytes are specific type of brain cells which are not electrically excitable but inducing chemical modulations of neuronal firing. We analyzed how the astrocytes influence on images encoded in the form of dynamic spiking pattern of the SNN.
arxiv   +1 more source

Characterization of Vimentin-Immunoreactive Astrocytes in the Human Brain

Frontiers in Neuroanatomy, 2020
Astrocytes are commonly identified by their expression of the intermediate filament protein glial fibrillary acidic protein (GFAP). GFAP-immunoreactive (GFAP-IR) astrocytes exhibit regional heterogeneity in density and morphology in the mouse brain as ...
Liam Anuj O’Leary, Liam Anuj O’Leary, Maria Antonietta Davoli, Claudia Belliveau, Claudia Belliveau, Arnaud Tanti, Jie Christopher Ma, William Todd Farmer, Gustavo Turecki, Gustavo Turecki, Gustavo Turecki, Keith Kazuo Murai, Naguib Mechawar, Naguib Mechawar, Naguib Mechawar   +14 more
doaj   +1 more source

Contextual guidance: An integrated theory for astrocytes function in brain circuits and behavior [PDF]

, 2022
The participation of astrocytes in brain computation was formally hypothesized in 1992, coinciding with the discovery that these glial cells display a complex form of Ca2+ excitability. This fostered conceptual advances centered on the notion of reciprocal interactions between neurons and astrocytes, which permitted a critical leap forward in ...
arxiv   +1 more source

Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy

Journal of Neuroinflammation, 2023
Objective Patients with hypertension have a risk of depression. Morinda officinalis oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to determine whether MOOs can improve the symptoms of depression in individuals with ...
Lixuan Yang, Yutian Ao, Yannan Li, Baoan Dai, Jingchun Li, Wenzhe Duan, Wei Gao, Zhonghui Zhao, Zhenyun Han, Rongjuan Guo   +9 more
doaj   +1 more source