Results 1 to 10 of about 462,755 (380)
Specialized astrocytes mediate glutamatergic gliotransmission in the CNS
Nature, 2023 A subpopulation of astrocytes selectively expresses synaptic-like glutamate-release machinery, actively secretes the transmitter and is localized to discrete sites in the hippocampus.
Roberta de Ceglia +2 more
exaly +2 more sources
An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells [PDF]
Stem Cell Reports, 2017 Summary: Growing evidence implicates the importance of glia, particularly astrocytes, in neurological and psychiatric diseases. Here, we describe a rapid and robust method for the differentiation of highly pure populations of replicative astrocytes from ...
Julia TCW +13 more
doaj +4 more sources
Astrocytes: biology and pathology
Acta Neuropathologica, 2009 Astrocytes are specialized glial cells that outnumber neurons by over fivefold. They contiguously tile the entire central nervous system (CNS) and exert many essential complex functions in the healthy CNS.
Michael V Sofroniew, Harry V Vinters
exaly +2 more sources
Disease-associated astrocytes in Alzheimer’s disease and aging
Nature Neuroscience, 2020 The role of non-neuronal cells in Alzheimer’s disease progression has not been fully elucidated. Using single-nucleus RNA sequencing, we identified a population of disease-associated astrocytes in an Alzheimer’s disease mouse model.
Naomi Habib +2 more
exaly +2 more sources
An update on reactive astrocytes in chronic pain
Journal of Neuroinflammation, 2019 Chronic pain is a critical clinical problem with an increasing prevalence. However, there are limited effective prevention measures and treatments for chronic pain.
Ting Li +4 more
doaj +2 more sources
Function and therapeutic value of astrocytes in neurological diseases
Nature Reviews Drug Discovery, 2022 Hong-Gyun Lee +2 more
exaly +2 more sources
Neurotoxic reactive astrocytes are induced by activated microglia
Nature, 2017 Shane A Liddelow +2 more
exaly +2 more sources
MAFG-driven astrocytes promote CNS inflammation
Nature, 2020 Michael A Wheeler +2 more
exaly +2 more sources
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
Nature, 2021 Michael A Wheeler +2 more
exaly +2 more sources
Cell-autonomous regulation of astrocyte activation by the circadian clock protein BMAL1 [PDF]
, 2018 Cedeno, Michelle R +11 more
core +4 more sources