Results 11 to 20 of about 462,755 (380)

Microglial control of astrocytes in response to microbial metabolites

Nature, 2018
Davis M Borucki, Chun-Cheih Chao, Kalil Alves de Lima   +2 more
exaly   +2 more sources

Metabolic Heterogeneity of Cerebral Cortical and Cerebellar Astrocytes

Life, 2023
Astrocytes play critical roles in regulating neuronal synaptogenesis, maintaining blood–brain barrier integrity, and recycling neurotransmitters. Increasing numbers of studies have suggested astrocyte heterogeneity in morphology, gene profile, and ...
Yuanhong Sun, Ali Winters, Linshu Wang, Kiran Chaudhari, Raymond Berry, Christina Tang, Ran Liu, Shaohua Yang   +7 more
doaj   +1 more source

Isolation of ferret astrocytes reveals their morphological, transcriptional, and functional differences from mouse astrocytes

Frontiers in Cellular Neuroscience, 2022
Astrocytes play key roles in supporting the central nervous system structure, regulating synaptic functions, and maintaining brain homeostasis. The number of astrocytes in the cerebrum has markedly increased through evolution.
Jureepon Roboon, Tsuyoshi Hattori, Dinh Thi Nguyen, Hiroshi Ishii, Mika Takarada-Iemata, Takayuki Kannon, Kazuyoshi Hosomichi, Takashi Maejima, Kengo Saito, Yohei Shinmyo, Michihiro Mieda, Atsushi Tajima, Hiroshi Kawasaki, Osamu Hori   +13 more
doaj   +1 more source

Human iPSC-derived APOE4/4 Alzheimer´s disease astrocytes exhibit a senescent and pro-inflammatory state that compromises neuronal support. [PDF]

J Neuroinflammation
Caceres-Palomo L, Sanchez-Mejias E, Trujillo-Estrada L, Perez-Moreno JJ, Lopez-Oliva E, Lim TE, DeFlitch L, Chang SH, Kampman L, Corces MR, Blurton-Jones M, Moreno-Gonzalez I, Pascual A, Vitorica J, Garcia-Leon JA, Gutierrez A.   +15 more
europepmc   +2 more sources

The origins and dynamic changes of C3- and S100A10-positive reactive astrocytes after spinal cord injury

Frontiers in Cellular Neuroscience, 2023
Accaumulating studies focus on the effects of C3-positive A1-like phenotypes and S100A10-positive A2-like phenotypes of reactive astrocytes on spinal cord injury (SCI), however the origins and dynamic changes of C3- and S100A10-positive reactive ...
Qing Zhao, Qing Zhao, Yi-long Ren, Yi-long Ren, Yan-jing Zhu, Rui-qi Huang, Rong-rong Zhu, Li-ming Cheng, Li-ming Cheng, Li-ming Cheng, Ning Xie, Ning Xie   +11 more
doaj   +1 more source

D1- and D2-type dopamine receptors are immunolocalized in pial and layer I astrocytes in the rat cerebral cortex

Frontiers in Neuroanatomy, 2023
Pial astrocytes, a cellular component of the cerebral cortex surface structure, are observed in a wide range of mammalian species. Despite being recognized as such, the functional potential of pial astrocytes has long been overlooked.
Satoko Oda, Hiromasa Funato, Hiromasa Funato   +2 more
doaj   +1 more source

Roles of neuropathology-associated reactive astrocytes: a systematic review

Acta Neuropathologica Communications, 2023
In the contexts of aging, injury, or neuroinflammation, activated microglia signaling with TNF-α, IL-1α, and C1q induces a neurotoxic astrocytic phenotype, classified as A1, A1-like, or neuroinflammatory reactive astrocytes.
J. Lawrence, Kayla Schardien, B. Wigdahl, M. Nonnemacher   +3 more
semanticscholar   +1 more source

Differential Proliferation and Maturation of Subcortical Astrocytes During Postnatal Development

Frontiers in Neuroscience, 2020
Astrocytes exhibit a region-dependent molecular and functional heterogeneity in the CNS. Although cortical astrocytes proliferate robustly during the first postnatal week and become proliferation quiescent, the temporal proliferation dynamics of ...
Temitope Shoneye, Alessandra Tamashiro Orrego, Rachel Jarvis, Yuqin Men, Ming Sum R. Chiang, Yongjie Yang, Yongjie Yang   +6 more
doaj   +1 more source

Brain Synapses: Neurons, Astrocytes, and Extracellular Vesicles in Health and Diseases. [PDF]

Int J Mol Sci
Meldolesi J.
europepmc   +3 more sources

Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. [PDF]

, 2014
Although astrocytes are the most abundant cell type in the central nervous system (CNS), little is known about their molecular specification and differentiation.
Chen, Yidan, Hu, Xuemei, Huang, Hao, Qiu, Mengsheng, Sander, Maike, Teng, Peng, Xie, Binghua, Zhang, Zunyi, Zhao, Xiaofeng, Zheng, Kang, Zhu, Qiang   +10 more
core   +10 more sources