Journal of Neuroinflammation, 2023 Objective Patients with hypertension have a risk of depression. Morinda officinalis oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to determine whether MOOs can improve the symptoms of depression in individuals with ...
Lixuan Yang +9 more
doaj +1 more source
The similarity of astrocytes number in dentate gyrus and CA3 subfield of rats hippocampus [PDF]
, 2007 The dentate gyrus is a part of hippocampal formation that it contains granule cells, which project to the pyramidal cells and interneurons of the CA3 subfield of the hippocampus.
Hosseini, A. +3 more
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Differential sensitivity of brainstem vs cortical astrocytes to changes in pH reveals functional regional specialization of astroglia [PDF]
, 2013 Astrocytes might function as brain interoceptors capable of detecting different (chemo)sensory modalities and transmitting sensory information to the relevant neural networks controlling vital functions.
Castaldo, C +6 more
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Olig2-Lineage Astrocytes: A Distinct Subtype of Astrocytes That Differs from GFAP Astrocytes
Frontiers in Neuroanatomy, 2018 Astrocytes are the most abundant glia cell type in the central nervous system (CNS), and are known to constitute heterogeneous populations that differ in their morphology, gene expression and function.
Kouko Tatsumi +10 more
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Unperturbed posttranscriptional regulatory Rev protein function and HIV-1 replication in astrocytes. [PDF]
PLoS ONE, 2014 Astrocytes protect neurons, but also evoke proinflammatory responses to injury and viral infections, including HIV. There is a prevailing notion that HIV-1 Rev protein function in astrocytes is perturbed, leading to restricted viral replication.
Ashok Chauhan
doaj +1 more source
A novel Rac1-GSPT1 signaling pathway controls astrogliosis following central nervous system injury [PDF]
, 2016 Astrogliosis (i.e. glial scar), which is comprised primarily of proliferated astrocytes at the lesion site and migrated astrocytes from neighboring regions, is one of the key reactions in determining outcomes after CNS injury.
Aiba, Atsu +12 more
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A roadmap to integrate astrocytes into Systems Neuroscience. [PDF]
, 2020 Systems neuroscience is still mainly a neuronal field, despite the plethora of evidence supporting the fact that astrocytes modulate local neural circuits, networks, and complex behaviors. In this article, we sought to identify which types of studies are
De Pittà, Maurizio +7 more
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Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes
Cell Reports, 2016 Growing evidence indicates important roles for astrocytes in neurodevelopment and diseases. However, astrocytes and their roles in these processes remain poorly understood.
E Tian +7 more
doaj +1 more source
Journal of Neuroinflammation, 2020 Background Evidence shows significant heterogeneity in astrocyte gene expression and function. We previously demonstrated that brain-derived neurotrophic factor (BDNF) exerts protective effects on whole brain primary cultured rat astrocytes treated with ...
Julieta Saba +7 more
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Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection [PDF]
, 2017 Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR) signaling regulates the responses of endothelial cells of the blood-brain barrier (BBB) during neurotropic viral infection.
Ali +23 more
core +3 more sources