An update on reactive astrocytes in chronic pain
Journal of Neuroinflammation, 2019 Chronic pain is a critical clinical problem with an increasing prevalence. However, there are limited effective prevention measures and treatments for chronic pain.
Ting Li +4 more
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Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain
Molecular Brain, 2021 We have reported that the transcription factor Olig2 labels a subpopulation of astrocytes (Olig2-astrocytes), which show distribution patterns different from those of GFAP-expressing astrocytes (GFAP-astrocytes) in the adult brain.
Kouko Tatsumi +8 more
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The preventive and treatment effect of Urtica dioica on astrocyte density in the CA1 and CA3 subfields of hippocampus in STZ induced diabetic rats [PDF]
, 2013 Several animal model studies have shown that Diabetes mellitus can affect on the activity of hippocampus astrocytes, but these studies reported controversial findings.
Afshar, M. +3 more
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G protein-coupled receptor signalling in astrocytes in health and disease: A focus on metabotropic glutamate receptors [PDF]
, 2012 Work published over the past 10–15 years has caused the neuroscience community to engage in a process of constant re-evaluation of the roles of glial cells in the mammalian central nervous system.
Bradley, Sophie J., Challiss, R.A. John
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Alterations of gene expression and glutamate clearance in astrocytes derived from an MeCP2-null mouse model of Rett syndrome. [PDF]
PLoS ONE, 2012 Rett syndrome (RTT) is a neurodevelopmetal disorder associated with mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. MeCP2-deficient mice recapitulate the neurological degeneration observed in RTT patients.
Yasunori Okabe +5 more
doaj +1 more source
Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury. [PDF]
, 2016 Traumatic brain injury (TBI) can result in tissue alterations distant from the site of the initial injury, which can trigger pathological changes within hippocampal circuits and are thought to contribute to long-term cognitive and neuropsychological ...
Ethell, Iryna M +5 more
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Alteration of dentate gyrus astrocytes in diabetic rats: Protective role of Urtica dioica [PDF]
, 2011 Diabetes mellitus can cause astrocytes alterations in the central nervous system. Urtica dioica (Nettle) is among several species listed for their use against diabetes in folk medicine.
Ghafari, S. +3 more
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Frontiers in Pharmacology, 2018 Under pathological conditions in the central nervous system (CNS), including spinal cord injury, astrocytes show detrimental effects against neurons.
Yoshitaka Tanie +3 more
doaj +1 more source
Applied Sciences, 2021 Astrocytes are known to regulate normal brain function. Monoamine oxidase B (MAO-B), an enzyme highly expressed in astrocytes, metabolizes dopamine (DA) and induces reactive oxygen species (ROS) production.
Shiori Akiyama +4 more
doaj +1 more source
Astrocyte glutamine synthetase : pivotal in health and disease [PDF]
, 2013 The multifunctional properties of astrocytes signify their importance in brain physiology and neurological function. In addition to defining the brain architecture, astrocytes are primary elements of brain ion, pH and neurotransmitter homoeostasis.
Parpura, Vladimir +2 more
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