Results 31 to 40 of about 123,114 (319)
Mechanosensory Signaling in Astrocytes [PDF]
The Journal of Neuroscience, 2020 Mechanosensitivity is a well-known feature of astrocytes, however, its underlying mechanisms and functional significance remain unclear. There is evidence that astrocytes are acutely sensitive to decreases in cerebral perfusion pressure and may function as intracranial baroreceptors, tuned to monitor brain blood flow.
Alexander V. Gourine +13 more
openaire +7 more sources
Disease-associated astrocytes in Alzheimer’s disease and aging
Nature Neuroscience, 2020 The role of non-neuronal cells in Alzheimer’s disease progression has not been fully elucidated. Using single-nucleus RNA sequencing, we identified a population of disease-associated astrocytes in an Alzheimer’s disease mouse model.
Naomi Habib +14 more
semanticscholar +1 more source
Unperturbed posttranscriptional regulatory Rev protein function and HIV-1 replication in astrocytes. [PDF]
PLoS ONE, 2014 Astrocytes protect neurons, but also evoke proinflammatory responses to injury and viral infections, including HIV. There is a prevailing notion that HIV-1 Rev protein function in astrocytes is perturbed, leading to restricted viral replication.
Ashok Chauhan
doaj +1 more source
Interaction of Microglia and Astrocytes in the Neurovascular Unit
Frontiers in Immunology, 2020 The interaction between microglia and astrocytes significantly influences neuroinflammation. Microglia/astrocytes, part of the neurovascular unit (NVU), are activated by various brain insults.
Lirong Liu +4 more
semanticscholar +1 more source
Journal of Neuroinflammation, 2020 Background Evidence shows significant heterogeneity in astrocyte gene expression and function. We previously demonstrated that brain-derived neurotrophic factor (BDNF) exerts protective effects on whole brain primary cultured rat astrocytes treated with ...
Julieta Saba +7 more
doaj +1 more source
Controlling the spontaneous firing behavior of a neuron with astrocyte [PDF]
, 2022 Mounting evidence in recent years suggests that astrocytes, a sub-type of glial cells, not only serve metabolic and structural support for neurons and synapses but also play critical roles in regulation of proper functioning of the nervous system.
arxiv +1 more source
The FASEB Journal, 2010 The amygdala is connected to numerous brain regions and is involved in complex behaviors such as survival and reproduction. This highly conserved brain region is sexually dimorphic in several species with the most dramatic differences found in the medial subregion.
Cynthia L. Jordan +2 more
openaire +4 more sources
Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis [PDF]
Nature, 2017 Astrocytes are complex glial cells with numerous fine cellular processes that infiltrate the neuropil and interact with synapses. The mechanisms that control the establishment of astrocyte morphology are unknown, and it is unclear whether impairing astrocytic infiltration of the neuropil alters synaptic connectivity.
Cagla Eroglu +10 more
openaire +2 more sources
Gatekeeping astrocyte identity [PDF]
eLife, 2022 New findings cast doubt on whether suppressing the RNA-binding protein PTBP1 can force astrocytes to become dopaminergic neurons.
Alexis Cooper, Benedikt Berninger
openaire +4 more sources
Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes
Cell Reports, 2016 Growing evidence indicates important roles for astrocytes in neurodevelopment and diseases. However, astrocytes and their roles in these processes remain poorly understood.
E Tian +7 more
doaj +1 more source