Results 31 to 40 of about 462,755 (380)

Olig2-Lineage Astrocytes: A Distinct Subtype of Astrocytes That Differs from GFAP Astrocytes

Frontiers in Neuroanatomy, 2018
Astrocytes are the most abundant glia cell type in the central nervous system (CNS), and are known to constitute heterogeneous populations that differ in their morphology, gene expression and function.
Kouko Tatsumi, Ayami Isonishi, Miwako Yamasaki, Yoshie Kawabe, Shoko Morita-Takemura, Kazuki Nakahara, Yuki Terada, Takeaki Shinjo, Hiroaki Okuda, Tatsuhide Tanaka, Akio Wanaka   +10 more
doaj   +1 more source

Astrocytes from cortex and striatum show differential responses to mitochondrial toxin and BDNF: implications for protection of striatal neurons expressing mutant huntingtin

Journal of Neuroinflammation, 2020
Background Evidence shows significant heterogeneity in astrocyte gene expression and function. We previously demonstrated that brain-derived neurotrophic factor (BDNF) exerts protective effects on whole brain primary cultured rat astrocytes treated with ...
Julieta Saba, Federico López Couselo, Juan Turati, Lila Carniglia, Daniela Durand, Andrea de Laurentiis, Mercedes Lasaga, Carla Caruso   +7 more
doaj   +1 more source

Unperturbed posttranscriptional regulatory Rev protein function and HIV-1 replication in astrocytes. [PDF]

PLoS ONE, 2014
Astrocytes protect neurons, but also evoke proinflammatory responses to injury and viral infections, including HIV. There is a prevailing notion that HIV-1 Rev protein function in astrocytes is perturbed, leading to restricted viral replication.
Ashok Chauhan
doaj   +1 more source

The preventive and treatment effect of Urtica dioica on astrocyte density in the CA1 and CA3 subfields of hippocampus in STZ induced diabetic rats [PDF]

, 2013
Several animal model studies have shown that Diabetes mellitus can affect on the activity of hippocampus astrocytes, but these studies reported controversial findings.
Afshar, M., Ghafari, S., Golalipour, M.J., Jahanshahi, M.   +3 more
core   +1 more source

Interaction of Microglia and Astrocytes in the Neurovascular Unit

Frontiers in Immunology, 2020
The interaction between microglia and astrocytes significantly influences neuroinflammation. Microglia/astrocytes, part of the neurovascular unit (NVU), are activated by various brain insults.
Lirong Liu, Jia-chen Liu, Jin-shuang Bao, Qinqin Bai, Gai-qing Wang   +4 more
semanticscholar   +1 more source

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology

Nature Communications, 2022
Alzheimer’s disease (AD) alters astrocytes, but the effect of Aß and Tau pathology is poorly understood. TRAP-seq translatome analysis of astrocytes in APP/PS1 ß-amyloidopathy and MAPTP301S tauopathy mice revealed that only Aß influenced expression of AD
Zoeb Jiwaji, S. S. Tiwari, R. X. Aviles-Reyes, Monique Hooley, D. Hampton, Megan Torvell, DelindaA . Johnson, Jamie McQueen, P. Baxter, Kayalvizhi Sabari-Sankar, J. Qiu, Xin He, Jill H. Fowler, James A Febery, Jenna M. Gregory, Jamie L. Rose, J. Tulloch, Jamie Loan, David J. Story, K. McDade, Amy M. Smith, Peta Greer, Matthew Ball, P. Kind, P. Matthews, Colin Smith, OR Dando, T. Spires-Jones, Jeffrey A. Johnson, S. Chandran, G. Hardingham   +30 more
semanticscholar   +1 more source

Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy

Journal of Neuroinflammation, 2023
Objective Patients with hypertension have a risk of depression. Morinda officinalis oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to determine whether MOOs can improve the symptoms of depression in individuals with ...
Lixuan Yang, Yutian Ao, Yannan Li, Baoan Dai, Jingchun Li, Wenzhe Duan, Wei Gao, Zhonghui Zhao, Zhenyun Han, Rongjuan Guo   +9 more
doaj   +1 more source

Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]

, 2012
As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S., Jahanshahi, M., Nickmahzar, E.   +2 more
core   +1 more source

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

Journal of Neuroscience, 2008
Understanding the cell–cell interactions that control CNS development and function has long been limited by the lack of methods to cleanly separate neural cell types.
John D. Cahoy, B. Emery, Amit Kaushal, L. Foo, Jennifer L Zamanian, K. S. Christopherson, Yi Xing, J. Lubischer, P. Krieg, S. Krupenko, W. Thompson, B. Barres   +11 more
semanticscholar   +1 more source

Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain

Molecular Brain, 2021
We have reported that the transcription factor Olig2 labels a subpopulation of astrocytes (Olig2-astrocytes), which show distribution patterns different from those of GFAP-expressing astrocytes (GFAP-astrocytes) in the adult brain.
Kouko Tatsumi, Kaoru Kinugawa, Ayami Isonishi, Masahiro Kitabatake, Hiroaki Okuda, Shoko Takemura, Tatsuhide Tanaka, Eiichiro Mori, Akio Wanaka   +8 more
doaj   +1 more source