Results 41 to 50 of about 303,608 (351)
Mechanosensory Signaling in Astrocytes [PDF]
The Journal of Neuroscience, 2020 Mechanosensitivity is a well-known feature of astrocytes, however, its underlying mechanisms and functional significance remain unclear. There is evidence that astrocytes are acutely sensitive to decreases in cerebral perfusion pressure and may function as intracranial baroreceptors, tuned to monitor brain blood flow.
Alexander V. Gourine +13 more
openaire +7 more sources
Gatekeeping astrocyte identity [PDF]
eLife, 2022 New findings cast doubt on whether suppressing the RNA-binding protein PTBP1 can force astrocytes to become dopaminergic neurons.
Alexis Cooper, Benedikt Berninger
openaire +4 more sources
Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis [PDF]
Nature, 2017 Astrocytes are complex glial cells with numerous fine cellular processes that infiltrate the neuropil and interact with synapses. The mechanisms that control the establishment of astrocyte morphology are unknown, and it is unclear whether impairing astrocytic infiltration of the neuropil alters synaptic connectivity.
Cagla Eroglu +10 more
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The FASEB Journal, 2010 The amygdala is connected to numerous brain regions and is involved in complex behaviors such as survival and reproduction. This highly conserved brain region is sexually dimorphic in several species with the most dramatic differences found in the medial subregion.
Cynthia L. Jordan +2 more
openaire +4 more sources
Journal of Integrative Neuroscience, 2022 The cellular, molecular and physiological basis of cognition has proved elusive until emerging studies on astrocytes. The appearance of a deliberate aggregating element in cellular neurophysiology was difficult to satisfy computationally with excitatory and inhibitory neuron physiology alone.
openaire +3 more sources
Applied Sciences, 2021 Astrocytes are known to regulate normal brain function. Monoamine oxidase B (MAO-B), an enzyme highly expressed in astrocytes, metabolizes dopamine (DA) and induces reactive oxygen species (ROS) production.
Shiori Akiyama +4 more
doaj +1 more source
Journal of Neuroscience, 2008 Understanding the cell–cell interactions that control CNS development and function has long been limited by the lack of methods to cleanly separate neural cell types.
John D. Cahoy +11 more
semanticscholar +1 more source
Astrocytes: a double-edged sword in neurodegenerative diseases
Neural Regeneration Research, 2021 Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the central nervous system by regulating homeostasis, increasing synaptic plasticity, and sustaining neuroprotective effects.
Z. Ding +5 more
semanticscholar +1 more source
Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes
Cell Reports, 2016 Growing evidence indicates important roles for astrocytes in neurodevelopment and diseases. However, astrocytes and their roles in these processes remain poorly understood.
E Tian +7 more
doaj +1 more source
Active sulforhodamine 101 uptake into hippocampal astrocytes. [PDF]
PLoS ONE, 2012 Sulforhodamine 101 (SR101) is widely used as a marker of astrocytes. In this study we investigated labeling of astrocytes by SR101 in acute slices from the ventrolateral medulla and the hippocampus of transgenic mice expressing EGFP under the control of ...
Christian Schnell +2 more
doaj +1 more source