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Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]

open access: yesChemistry – A European Journal, 2016
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima   +4 more
core   +10 more sources

Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes [PDF]

open access: yesMolecules, 2017
The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes is a very interesting tool for the construction of highly functionalized synthetic building blocks.
Diego A. Alonso   +6 more
doaj   +4 more sources

Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis [PDF]

open access: yesMolecules, 2013
The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations.
Isidro M. Pastor   +3 more
doaj   +8 more sources

Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2012
Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.
Pankaj Chauhan, Swapandeep Singh Chimni
doaj   +5 more sources

The Emergence of Quinone Methides in Asymmetric Organocatalysis [PDF]

open access: yesMolecules, 2015
Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry.
Lorenzo Caruana   +2 more
doaj   +4 more sources

Evolution of asymmetric organocatalysis : multi- and retrocatalysis [PDF]

open access: yesGreen Chemistry, 2012
The evolution of organocatalysis led to various valuable approaches, such as multicomponent as well as domino and tandem reactions. Recently, organomulticatalysis, i.e., the modular combination of distinct organocatalysts enabling consecutive reactions ...
Schreiner, Peter R., Wende, Raffael C.
core   +6 more sources

Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists

open access: yesMolecules, 2022
Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes   +2 more
doaj   +4 more sources

Do We Need Asymmetric Organocatalysis?

open access: yesCHIMIA, 2007
Asymmetric organocatalysis is a 'fast lane' of the chemical highway: the progress in the last decade is simply spectacular. This introductory article summarizes basic principles, historical background, and discusses basic catalyst classes and ...
Peter I. Dalko
doaj   +5 more sources

Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2016
Cinchona alkaloids with a free 6'-OH functionality are being increasingly used within asymmetric organocatalysis. This fascinating class of bifunctional catalyst offers a genuine alternative to the more commonly used thiourea systems and because of the ...
Laura A. Bryant   +2 more
doaj   +3 more sources

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