Results 1 to 10 of about 29,947 (175)
Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima+4 more
core +10 more sources
Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes [PDF]
The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes is a very interesting tool for the construction of highly functionalized synthetic building blocks.
Diego A. Alonso+6 more
doaj +4 more sources
Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis [PDF]
The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations.
Isidro M. Pastor+3 more
doaj +8 more sources
Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach [PDF]
Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.
Pankaj Chauhan, Swapandeep Singh Chimni
doaj +5 more sources
The Emergence of Quinone Methides in Asymmetric Organocatalysis [PDF]
Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry.
Lorenzo Caruana+2 more
doaj +4 more sources
New advances in asymmetric organocatalysis [PDF]
Radovan Šebesta
doaj +3 more sources
Evolution of asymmetric organocatalysis : multi- and retrocatalysis [PDF]
The evolution of organocatalysis led to various valuable approaches, such as multicomponent as well as domino and tandem reactions. Recently, organomulticatalysis, i.e., the modular combination of distinct organocatalysts enabling consecutive reactions ...
Schreiner, Peter R., Wende, Raffael C.
core +6 more sources
Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists
Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes+2 more
doaj +4 more sources
Do We Need Asymmetric Organocatalysis?
Asymmetric organocatalysis is a 'fast lane' of the chemical highway: the progress in the last decade is simply spectacular. This introductory article summarizes basic principles, historical background, and discusses basic catalyst classes and ...
Peter I. Dalko
doaj +5 more sources
Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts [PDF]
Cinchona alkaloids with a free 6'-OH functionality are being increasingly used within asymmetric organocatalysis. This fascinating class of bifunctional catalyst offers a genuine alternative to the more commonly used thiourea systems and because of the ...
Laura A. Bryant+2 more
doaj +3 more sources