Results 11 to 20 of about 31,425 (239)

Electrostatic Interactions in Asymmetric Organocatalysis [PDF]

open access: yesAccounts of Chemical Research, 2023
Electrostatic interactions are ubiquitous in catalytic systems and are often decisive in determining reactivity and stereoselectivity. However, a lack of understanding of the fundamental underlying principles has long stymied our ability to fully harness the power of these interactions.
Rajat Maji   +2 more
openaire   +3 more sources

Recent Developments and Trends in Asymmetric Organocatalysis [PDF]

open access: yesEuropean Journal of Organic Chemistry, 2022
AbstractAsymmetric organocatalysis has experienced a long and spectacular way since the early reports over a century ago by von Liebig, Knoevenagel and Bredig, showing that small (chiral) organic molecules can catalyze (asymmetric) reactions. This was followed by impressive first highly enantioselective reports in the second half of the last century ...
Olga García Mancheño, Mario Waser
openaire   +4 more sources

Advances in asymmetric organocatalysis over the last 10 years [PDF]

open access: yesNature Communications, 2020
Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as ...
Shao-Hua Xiang, Bin Tan
doaj   +2 more sources

Cross-trienamines in Asymmetric Organocatalysis [PDF]

open access: yesJournal of the American Chemical Society, 2012
AbstractCross‐conjugated trienamines are introduced as a new concept in asymmetric organocatalysis.
Halskov, Kim Søholm   +5 more
openaire   +5 more sources

Asymmetric Organocatalysis at the Service of Medicinal Chemistry [PDF]

open access: yesISRN Organic Chemistry, 2014
The application of the most representative and up-to-date examples of homogeneous asymmetric organocatalysis to the synthesis of molecules of interest in medicinal chemistry is reported. The use of different types of organocatalysts operative via noncovalent and covalent interactions is critically reviewed and the possibility of running some of these ...
Ricci A.
openaire   +3 more sources

Oxadendralenes in asymmetric organocatalysis for the construction of tetrahydroisochromenes [PDF]

open access: yesChemical Science, 2016
Oxadendralenes are integrated in a novel manner into a one-pot cascade utilizing synergistic catalysis for the construction of valuable and complex bicyclic heterocyclic scaffolds.
Hammer, Niels   +4 more
openaire   +6 more sources

Recent advances in organocatalytic atroposelective reactions [PDF]

open access: yesBeilstein Journal of Organic Chemistry
Axial chirality is present in a variety of naturally occurring compounds, and is becoming increasingly relevant also in medicine. Many axially chiral compounds are important as catalysts in asymmetric catalysis or have chiroptical properties. This review
Henrich Szabados, Radovan Šebesta
doaj   +2 more sources

Asymmetric Synthesis of 2-Arylethylamines: A Metal-Free Review of the New Millennium [PDF]

open access: yesMolecules
2-Arylethylamines are presented in several natural bioactive compounds, as well as in nitrogen-containing drugs. Their ability to surpass the blood–brain barrier makes this family of compounds of especial interest in medicinal chemistry.
Alejandro Manchado   +4 more
doaj   +2 more sources

Recent Advances in the Enantioselective Radical Reactions

open access: yesMolecules, 2023
The review covers research published since 2017 and is focused on enantioselective synthesis using radical reactions. It describes recent approaches to the asymmetric synthesis of chiral molecules based on the application of the metal catalysis, dual ...
Tomasz Bauer   +2 more
doaj   +1 more source

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