Results 11 to 20 of about 1,833 (153)
New advances in asymmetric organocatalysis II [PDF]
Beilstein Journal of Organic ChemistryRadovan Šebesta
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Electrostatic Interactions in Asymmetric Organocatalysis. [PDF]
Acc Chem Res, 2023 Electrostatic interactions are ubiquitous in catalytic systems and are often decisive in determining reactivity and stereoselectivity. However, a lack of understanding of the fundamental underlying principles has long stymied our ability to fully harness the power of these interactions.
Maji R, Mallojjala SC, Wheeler SE.
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Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists [PDF]
Molecules, 2022 Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes +2 more
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Advances in asymmetric organocatalysis over the last 10 years [PDF]
Nature Communications, 2020 Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as ...
Shao-Hua Xiang, Bin Tan
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Recent Developments and Trends in Asymmetric Organocatalysis. [PDF]
European J Org Chem, 2023 AbstractAsymmetric organocatalysis has experienced a long and spectacular way since the early reports over a century ago by von Liebig, Knoevenagel and Bredig, showing that small (chiral) organic molecules can catalyze (asymmetric) reactions. This was followed by impressive first highly enantioselective reports in the second half of the last century ...
García Mancheño O, Waser M.
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Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach [PDF]
Beilstein Journal of Organic Chemistry, 2012 Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.
Pankaj Chauhan, Swapandeep Singh Chimni
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Cross-trienamines in asymmetric organocatalysis. [PDF]
J Am Chem Soc, 2012 Cross-conjugated trienamines are introduced as a new concept in asymmetric organocatalysis. These intermediates are applied in highly enantioselective Diels-Alder and addition reactions, providing functionalized bicyclo[2.2.2]octane compounds and γ'-addition products, respectively.
Halskov KS +5 more
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Asymmetric organocatalysis involving double activation
Tetrahedron Chem, 2022 Asymmetric organocatalysis contributed tremendously to the field of organic synthesis since year 2000. Considering the diversity of organocatalysts and their activation modes, chemists developed the double activation strategy, in which two distinct ...
Zhi Chen +3 more
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The Emergence of Quinone Methides in Asymmetric Organocatalysis [PDF]
Molecules, 2015 Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry.
Lorenzo Caruana +2 more
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Enantioselective radical chemistry: a bright future ahead [PDF]
Beilstein Journal of Organic ChemistryThis perspective is focused on enantioselective free radical reactions. It describes several important catalytic asymmetric strategies applied to enantioselective radical reactions, including chiral Lewis acid catalysis, organocatalysis, photoredox ...
Anna C. Renner +3 more
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