Results 11 to 20 of about 2,455 (178)
New advances in asymmetric organocatalysis [PDF]
Beilstein Journal of Organic Chemistry, 2022 Radovan Šebesta
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Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists [PDF]
Molecules, 2022 Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes +2 more
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Advances in asymmetric organocatalysis over the last 10 years [PDF]
Nature Communications, 2020 Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as ...
Shao-Hua Xiang, Bin Tan
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Recent Developments and Trends in Asymmetric Organocatalysis [PDF]
European Journal of Organic Chemistry, 2022 AbstractAsymmetric organocatalysis has experienced a long and spectacular way since the early reports over a century ago by von Liebig, Knoevenagel and Bredig, showing that small (chiral) organic molecules can catalyze (asymmetric) reactions. This was followed by impressive first highly enantioselective reports in the second half of the last century ...
Olga García Mancheño, Mario Waser
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Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach [PDF]
Beilstein Journal of Organic Chemistry, 2012 Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.
Pankaj Chauhan, Swapandeep Singh Chimni
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Cross-trienamines in Asymmetric Organocatalysis [PDF]
Journal of the American Chemical Society, 2012 Cross-conjugated trienamines are introduced as a new concept in asymmetric organocatalysis. These intermediates are applied in highly enantioselective Diels-Alder and addition reactions, providing functionalized bicyclo[2.2.2]octane compounds and γ'-addition products, respectively.
Halskov, Kim Søholm +5 more
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Asymmetric Conjugate Hydrocyanation of α,β-Unsaturated Aldehydes Catalyzed by Engineered 2-Deoxy-D-ribose-5-phosphate Aldolase. [PDF]
ChemistryThe power of catalytic promiscuity: The enantioselective conjugate hydrocyanation of enals remains a long‐standing challenge for biocatalysis. Here, we report the redesign of 2‐deoxy‐D‐ribose‐5‐phosphate aldolase for the asymmetric conjugate hydrocyanation of aromatic enals, expanding the reaction scope of iminium‐based enzyme catalysis to include an ...
Zhou H, Fodran P, Fu H, Poelarends GJ.
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Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis [PDF]
ChemSusChem, 2021 Achille Antenucci +2 more
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Enantioselective radical chemistry: a bright future ahead [PDF]
Beilstein Journal of Organic ChemistryThis perspective is focused on enantioselective free radical reactions. It describes several important catalytic asymmetric strategies applied to enantioselective radical reactions, including chiral Lewis acid catalysis, organocatalysis, photoredox ...
Anna C. Renner +3 more
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Cinchona Alkaloids in Asymmetric Organocatalysis [PDF]
Synthesis, 2012 This article reviews the applications of cinchona alkaloids as asymmetric catalysts. In the last few years, characterized by the resurgence of interest in asymmetric organocatalysis, cinchona derivatives have been shown to catalyze an outstanding array of chemical reactions, often with remarkable stereoselectivity. This work presents an overview of the
Tommaso Marcelli, Henk Hiemstra
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