Results 51 to 60 of about 2,455 (178)

Catalytic Asymmetric Amino Acid and Its Derivatives by Chiral Aldehyde Catalysis

Frontiers in Chemistry, 2021
Amine acid transformation is an important chemical process in biological systems. As a well-developed and acknowledged tool, chiral aldehyde catalysis provides good catalytic activation and stereoselective control abilities in the asymmetric reaction of ...
Kaijin Lin, Ang Shi, Chunhong Shi, Jinbiao Lin, Honggui Lin   +4 more
doaj   +1 more source

Catalytic Strategies for Amide‐Based Michael Additions: Advances and Perspectives

Journal of Chemistry, Volume 2026, Issue 1, 2026.
The Michael addition is a cornerstone transformation in organic synthesis, enabling efficient C–C and C–heteroatom bond formation. Traditionally, α,β‐unsaturated carbonyl compounds such as enones and esters have dominated as Michael acceptors, whereas α,β‐unsaturated amides remain underutilized due to their strong resonance stabilization and low ...
Muhammad Naufal, Elvira Hermawati, Ace Tatang Hidayat, Dadan Sumiarsa, Ika Wiani Hidayat, Jamaludin Al-Anshori, Tulika Banerjee   +6 more
wiley   +1 more source

Evolution in the Test-Tube as a Means to Create Selective Biocatalysts

CHIMIA, 2007
The development of chiral catalysts for use in synthetic organic chemistry is traditionally associated with progress in asymmetric transition metal catalysis or organocatalysis.
Manfred T. Reetz
doaj   +1 more source

Evolution of asymmetric organocatalysis: multi- and retrocatalysis [PDF]

Green Chemistry, 2012
The evolution of organocatalysis led to various valuable approaches, such as multicomponent as well as domino and tandem reactions. Recently, organomulticatalysis, i.e., the modular combination of distinct organocatalysts enabling consecutive reactions to be performed in one pot, has become a powerful tool in organic synthesis.
Wende, Raffael C., Schreiner, Peter R., Justus Liebig University Giessen   +2 more
openaire   +3 more sources

Fluxional Halogen Bonds Versus Interlayer Stacking – Theory Meets Experiment

Chemistry – A European Journal, Volume 31, Issue 70, December 12, 2025.
Joint high‐resolution X‐ray diffraction and density functional theory investigations reveal the existence of fluxional halogen bonds in the cocrystal of 1,4‐diiodobenzene and 1,4‐dinitrobenzene. At 130 K this solid undergoes a reversible crystal‐to‐crystal phase transition from the high‐temperature 1α phase with a symmetric bifurcated halogen bond to a
Cai Yue Gao, Annika Schmidt, Ruimin Wang, Carsten Strohmann, Ulli Englert, Si‐Dian Li   +5 more
wiley   +1 more source

Cooperative Photocatalysis of 9,10‐Phenanthrenequinone and Sn(OTf)2 for Direct Mannich Reaction of Ethers via Hydrogen Atom Transfer Pathway

Advanced Synthesis &Catalysis, Volume 367, Issue 23, December 11, 2025.
A dual photocatalytic system of o‐PQ and Sn(OTf)2 enables visible light‐induced Mannich‐type addition of ethers to nitrones via Csp³–H activation. This oxidant‐free method offers broad scope and good yields. Mechanistic studies suggest that a photoexcited o‐PQ–Sn(II) complex mediates hydrogen atom transfer to form α‐oxy radicals for nitrone addition. A
Pradip Ramdas Thorve, Hun Young Kim, Kyungsoo Oh   +2 more
wiley   +1 more source

ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES

Química Nova
In the last two decades, enantioselective organocatalysis has established itself as one of the three pillars of asymmetric catalysis. The rapid growth in the area is due to the rationalization of organocatalysis based on the generic modes of catalyst ...
Fernanda G. Finelli, Bruno M. da S. Santos, Lívia C. R. M. da Frota   +2 more
doaj   +1 more source

Installation of Trifluoromethylated Quaternary Carbon Stereocenters via Asymmetric Epoxidation of Tetrasubstituted Alkenes

Advanced Synthesis &Catalysis, Volume 367, Issue 23, December 11, 2025.
The catalytic enantioselective epoxidation of acyclic tetrasubstituted alkenes, bearing a trifluoromethyl group, is reported. In the presence of Takemoto's thiourea organocatalyst and tert‐butyl hydroperoxide, epoxides are obtained with excellent yield and good to high enantioselectivity.
Vincenzo Battaglia, Isaac G. Sonsona, Andrea Pellegrini, Andrea Mazzanti, Alessandra Lattanzi   +4 more
wiley   +1 more source

Total Asymmetric Synthesis of Monosaccharides and Analogues

CHIMIA, 2011
Since the discovery of the 'formose reaction' by Butlerow,[1] total synthesis of carbohydrates has undergone rapid development. The most important methods for the asymmetric synthesis of monosaccharides and analogues of biological importance are
Inmaculada Robina, Ana T. Carmona, Antonio J. Moreno-Vargas, Elena Moreno-Clavijo   +3 more
doaj   +1 more source

Dearomative Higher‐Order Cycloaddition for the Construction of Dihydropyrimidin‐4(1H)‐One Scaffold Employing N‐Heterocyclic Carbene Catalysis

Advanced Synthesis &Catalysis, Volume 367, Issue 23, December 11, 2025.
The study presents dearomative higher‐order cycloaddition as an effective strategy for constructing the biologically important dihydropyrimidin‐4(1H)‐one core. The method employs indole‐7‐carbaldehydes as precursors of higherenes, which, under N‐heterocyclic carbene (NHC) catalysis, generate NHC‐bound aza‐o‐quinodimethanes.
Adam Cieśliński, Artur Przydacz, Anna Skrzyńska, Łukasz Albrecht   +3 more
wiley   +1 more source