Results 51 to 60 of about 1,833 (153)

Catalytic Asymmetric Amino Acid and Its Derivatives by Chiral Aldehyde Catalysis

Frontiers in Chemistry, 2021
Amine acid transformation is an important chemical process in biological systems. As a well-developed and acknowledged tool, chiral aldehyde catalysis provides good catalytic activation and stereoselective control abilities in the asymmetric reaction of ...
Kaijin Lin, Ang Shi, Chunhong Shi, Jinbiao Lin, Honggui Lin   +4 more
doaj   +1 more source

Evolution in the Test-Tube as a Means to Create Selective Biocatalysts

CHIMIA, 2007
The development of chiral catalysts for use in synthetic organic chemistry is traditionally associated with progress in asymmetric transition metal catalysis or organocatalysis.
Manfred T. Reetz
doaj   +1 more source

Evolution of asymmetric organocatalysis: multi- and retrocatalysis [PDF]

Green Chemistry, 2012
The evolution of organocatalysis led to various valuable approaches, such as multicomponent as well as domino and tandem reactions. Recently, organomulticatalysis, i.e., the modular combination of distinct organocatalysts enabling consecutive reactions to be performed in one pot, has become a powerful tool in organic synthesis.
Wende, Raffael C., Schreiner, Peter R., Justus Liebig University Giessen   +2 more
openaire   +3 more sources

ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES

Química Nova
In the last two decades, enantioselective organocatalysis has established itself as one of the three pillars of asymmetric catalysis. The rapid growth in the area is due to the rationalization of organocatalysis based on the generic modes of catalyst ...
Fernanda G. Finelli, Bruno M. da S. Santos, Lívia C. R. M. da Frota   +2 more
doaj   +1 more source

Total Asymmetric Synthesis of Monosaccharides and Analogues

CHIMIA, 2011
Since the discovery of the 'formose reaction' by Butlerow,[1] total synthesis of carbohydrates has undergone rapid development. The most important methods for the asymmetric synthesis of monosaccharides and analogues of biological importance are
Inmaculada Robina, Ana T. Carmona, Antonio J. Moreno-Vargas, Elena Moreno-Clavijo   +3 more
doaj   +1 more source

Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts

Beilstein Journal of Organic Chemistry, 2016
Cinchona alkaloids with a free 6'-OH functionality are being increasingly used within asymmetric organocatalysis. This fascinating class of bifunctional catalyst offers a genuine alternative to the more commonly used thiourea systems and because of the ...
Laura A. Bryant, Rossana Fanelli, Alexander J. A. Cobb   +2 more
doaj   +1 more source

The Use of N-iPr-2,2'-bipyrrolidine Derivatives as Organocatalysts for Asymmetric Michael Additions

CHIMIA, 2006
The recent rapid growth of organocatalysis has shown a new approach in organic chemistry and presents the obvious advantage in the avoidance of expensive and often toxic metals.
Sarah Mossé, Olivier Andrey, Alexandre Alexakis   +2 more
doaj   +1 more source

Reações de organocatálise com aminas quirais: aspectos mecanísticos e aplicações em síntese orgânica Organocatalysis reactions with chiral amines: mechanistic aspects and use on organic synthesis

Química Nova, 2009
The philosophy of organocatalysis is based on the utilization of organic compounds to catalyze organic transformations without the intervention of metals.
Giovanni W. Amarante, Fernando Coelho
doaj   +1 more source

Enantioselective α-heterofunctionalization reactions of catalytically generated C1-Lewis base enolates

Tetrahedron Chem
Chiral Lewis base (LB) organocatalysis has emerged as a powerful covalent catalysis concept which allows for highly selective asymmetric C–C and C-heteroatom bond formations.
Magdalena Piringer, Lotte Stockhammer, Lukas Vogl, David Weinzierl, Paul Zebrowski, Mario Waser   +5 more
doaj   +1 more source

Asymmetric Synthesis of 2-Arylethylamines: A Metal-Free Review of the New Millennium

Molecules
2-Arylethylamines are presented in several natural bioactive compounds, as well as in nitrogen-containing drugs. Their ability to surpass the blood–brain barrier makes this family of compounds of especial interest in medicinal chemistry.
Alejandro Manchado, Ángel García-González, Carlos T. Nieto, David Díez, Narciso M. Garrido   +4 more
doaj   +1 more source