Results 11 to 20 of about 3,123,489 (311)
Asymmetric Synthesis of Cycloartobiloxanthone. [PDF]
Org LettHerein, we report the first asymmetric synthesis of cycloartobiloxanthone, a polycyclic dihydroxanthone natural product. Our convergent synthesis employs a rhodium-catalyzed C-H insertion reaction to construct the key fused tricyclic core with high enantioselectivity.
Hsieh CE +8 more
europepmc +3 more sources
Collective Asymmetric Total Synthesis of Cylindricines [PDF]
, 2023 Collective asymmetric total synthesis of marine tricyclic alkaloids, cylindricines A–H, and the proposed structures of cylindricine I and J, was achieved in a concise manner from a single common spirocyclic pyrrolidine intermediate.
Haruhiko, Fuwa +3 more
core +2 more sources
Synthesis of pyran and related natural products [PDF]
, 2012 This study was aimed at preparing dihydropyrans (DHPs) for the synthesis of 2,6-disubstituted tetrahydropyrans (THPs) in a diastereoselective manner. In an attempt to develop a novel methodology for the synthesis of DHPs from δ-hydroxy-β-ketoester and ...
Yeung, Bun
core +5 more sources
Asymmetric Synthesis of Ageliferin [PDF]
Journal of the American Chemical Society, 2011 We describe herein an asymmetric synthesis of ageliferin. A Mn(III)-mediated oxidative radical cyclization reaction was used as the key step to construct the core skeleton of this pyrrole-imidazole dimer. This approach resembles the biogenic [4 + 2] dimerization in an intramolecular fashion.
Xiao, Wang +4 more
openaire +2 more sources
Asymmetric synthesis of nortropanes via Rh-catalysed allylic arylation [PDF]
, 2022 Tropane derivatives are extensively used in medicine, but catalytic asymmetric methods for their synthesis are underexplored. Here we report Rh-catalysed asymmetric Suzuki-Miyaura type cross coupling reactions between a racemic N-Boc-nortropane-derived ...
Stephen P., Fletcher +7 more
core +2 more sources
Asymmetric synthesis of (−)-naltrexone
Chemical Science, 2019 The asymmetric synthesis of (−)-naltrexone was achieved by a Rh( i )-catalyzed C–H alkenylation and torquoselective electrocyclization cascade and late-stage C–H hydroxylation.
Sun Dongbang +2 more
openaire +3 more sources
Asymmetric Synthesis of Griffipavixanthone Employing a Chiral Phosphoric Acid-Catalyzed Cycloaddition [PDF]
, 2018 Asymmetric synthesis of the biologically active xanthone dimer griffipavixanthone (GPX) is reported along with its absolute stereochemistry determination.
Thomas, Heavey +6 more
core +1 more source
Asymmetric methodologies for the construction of 5,7,5- and 6,6,6-tricyclic sesquiterpene lactones towards the synthesis of Arglabin [PDF]
, 2007 Many naturally extracted guaianolides (i.e. GLs) and pseudoguaianolides are based on the 5,7,5-fused ring skeleton and they show a broad biological profile. Among them, Arglabin has attracted special attention due to its promising antitumor and cytotoxic
Jeong, Won Boo
core +1 more source
Comptes Rendus. Chimie, 2021 7-Cyano-15-methoxy[6]helicene was synthesized, in 54% overall yield, through a short photochemical procedure including mild conditions and inexpensive reagents.
Hafedh, Nesrine +2 more
doaj +1 more source
In Vivo Nanodetoxication for Acute Uranium Exposure
Molecules, 2015 Accidental exposure to uranium is a matter of concern, as U(VI) is nephrotoxic in both human and animal models, and its toxicity is associated to chemical toxicity instead of radioactivity. We synthesized different PAMAM G4 and G5 derivatives in order to
Luis Guzmán +4 more
doaj +1 more source