Results 51 to 60 of about 449,894 (327)
The totally asymmetric exclusion process with extended objects, a model for protein synthesis [PDF]
Phys. Rev. E 68, 021910 (2003), 2003 The process of protein synthesis in biological systems resembles a one dimensional driven lattice gas in which the particles have spatial extent, covering more than one lattice site. We expand the well studied Totally Asymmetric Exclusion Process (TASEP), in which particles typically cover a single lattice site, to include cases with extended objects ...
arxiv +1 more source
Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019) [PDF]
, 2019 The broad interdisciplinary nature of biocatalysis fosters innovation, as different technical fields are interconnected and synergized. A way to depict that innovation is by conducting a survey on patent activities.
Alcántara, Andrés R. +2 more
core +3 more sources
Aggregation-Induced Synthesis (AIS): Asymmetric Synthesis via Chiral Aggregates
Research, 2022 A new chiral aggregate-based tool for asymmetric synthesis has been developed by taking advantage of chiral aggregates of GAP (Group-Assisted Purification) reagents, N-phosphonyl imines.
Hossein Rouh +11 more
doaj +1 more source
Asymmetric enzyme kinetics of F1-ATPase induced by rotation-assisted substrate binding [PDF]
Phys. Rev. Research 7, 023213 (2025)We demonstrate asymmetric enzyme kinetics of a biomolecular motor F1-ATPase between synthesis and hydrolysis of adenosine triphosphate (ATP). Our experiments show that ATP hydrolysis follows Michaelis-Menten kinetics, but ATP synthesis, which is an F1-ATPase's primary biological role, deviates from it. Specifically, the synthesis rate is sustained even
arxiv +1 more source
Fourier synthesis of optical potentials for atomic quantum gases [PDF]
Phys. Rev. A 74, 063622 (2006), 2005 We demonstrate a scheme for the Fourier synthesis of periodic optical potentials with asymmetric unit cells for atoms. In a proof of principle experiment, an atomic Bose-Einstein condensate is exposed to either symmetric or sawtooth-like asymmetric potentials by superimposing a conventional standing wave potential of $\lambda/2$ spatial periodicity ...
arxiv +1 more source
Formal Synthesis of the Anti-Angiogenic Polyketide (-)-Borrelidin under Asymmetric Catalytic Control [PDF]
, 2010 Borrelidin (1) is a polyketide that possesses extremely potent anti-angiogenesis activity. This paper describes its formal total synthesis by the most efficient route to date.
Madduri, Ashoka V. R. +1 more
core +3 more sources
Optimized Asymmetric Synthesis of Umuravumbolide
ACS Omega, 2022 Herein, the asymmetric synthesis of umuravumbolide (1) is described. The new approach features highly stereoselective transformations (dr ≥ 95:5) to install both stereocenters and the Z olefin, which involve a new radical alkylation, an Ando olefination, and a Krische allylation on a Z allylic alcohol, not reported before.
Marina Pérez-Palau +3 more
openaire +3 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Stereocontrolled asymmetric synthesis [PDF]
Pure and Applied Chemistry, 2000 Abstract Stereo differentiated asymmetric syntheses have been achieved by S-indoline derivations. Diels-Alder cycloadditions of S-indoline chiral acrylamides with cyclopentadiene proceed with high diastereofacial selectivity, giving either endo-R or endo-S products depending on Lewis acid and the structures of chiral dienophiles ...
y. h kim Kim, Yong Hae +3 more
openaire +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source