Results 121 to 130 of about 24,420 (229)

Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype

The Journal of Physiology, Volume 604, Issue 11, Page 4166-4185, 1 June 2026.
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido, Claudia Reyes‐Goya, Pablo Espinosa‐Martín, Rosa M. Troya‐Toledo, Helder André, Alfonso Mate, Carmen M. Vázquez   +6 more
wiley   +1 more source

Telmisartan Potentiates Insulin Secretion via Ion Channels, Independent of the AT1 Receptor and PPARγ. [PDF]

Front Pharmacol, 2021
Liu T, Cui L, Xue H, Yang X, Liu M, Zhi L, Yang H, Liu Z, Zhang M, Guo Q, He P, Liu Y, Zhang Y.   +12 more
europepmc   +1 more source

Agonistic autoantibodies directed against the angiotensin II At1 receptor in patients with preeclampsia

, 2003
We showed that sera from patients with preeclampsia contain autoantibodies directed against the angiotensin II AT1 receptor. The antibodies recognize an epitope on the second extracellular loop of the receptor and are immunoglobulins of the IgG3 subclass.
Nissen, E., Homuth, V., Neichel, D., Luft, F.C., Wallukat, G.   +4 more
core   +1 more source

Acute GLP‐1 infusion in male adults lowers circulating angiotensin II without changing angiotensinogen, ACE, ACE2, or angiotensin‐(1–7) concentrations

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists elicit cardiovascular and renal protection. In humans, GLP‐1 reduces plasma angiotensin II (ANGII) and increases renal perfusion, leading to increased natriuresis. The mechanisms underlying suppression of ANGII remain unclear but may involve ACE2 activation and/or a decrease in angiotensinogen.
Ali Asmar, Muskaan Akram, Charlotte M. Sorensen, Jesper K. Andresen, Boye L. Jensen   +4 more
wiley   +1 more source

Emerging Benefits of AT1 Receptor Antagonists With Pleiotropic Anti-Inflammatory Activity

, 2011
In summary, angiotensin receptor antagonists with pleiotropic properties, such as telmisartan, have a great deal to recommend them in the treatment of the metabolic syndrome: they are antihypertensive, anti-inflammatory, may lower blood glucose ...
L. Brown, C. Sernia, Brown, Lindsay, Sernia, Conrad   +3 more
core   +1 more source

Sarcosine1,glycine8 angiotensin II is an AT1 angiotensin II receptor subtype selective antagonist

, 2003
Studies predating the discovery of the two major subtypes of angiotensin II (Ang II) receptors, AT1 and AT2, revealed anomalous characteristics of sarcosine1,glycine8 Ang II (Sar1,Gly8 Ang II).
Speth, Robert C
core   +1 more source

Immunohistochemical localization of rat angiotensin II AT1 receptor

, 1993
To study receptors for angiotensin II, polyclonal rabbit anti-peptide antisera were prepared against the peptide QDDCPKAGRHC corresponding to amino acids 15-24 of the rat AT1A and AT1B receptors.
M. Runge, C. Horaist, W. G. Paxton, C. Cohen, K. E. Bernstein, R. W. Alexander   +5 more
core   +1 more source

Effect of potassium depletion on proximal tubule AT1 receptor localization in normal and remnant rat kidney

, 2001
Effect of potassium depletion on proximal tubule AT1 receptor localization in normal and remnant rat kidney.BackgroundSince both potassium depletion and renal ablation result in proximal tubule hypertrophy and the angiotensin II type 1 (AT1) receptor has
Ghorbani, Masoud, Levine, David Z., Burns, Kevin D., Fryer, James N.   +3 more
core   +1 more source

Angiotensin II prompts heart cell apoptosis via AT1 receptor-augmented phosphatase and tensin homolog and miR-320-3p functions to enhance suppression of the IGF1R-PI3K-AKT survival pathway. [PDF]

J Hypertens, 2022
Lu SY, Hong WZ, Tsai BC, Chang YC, Kuo CH, Mhone TG, Chen RJ, Kuo WW, Huang CY.   +8 more
europepmc   +1 more source

Valsartan Prevented Neointimal Hyperplasia and Inhibited SRSF1 Expression and the TLR4-iNOS-ERK-AT1 Receptor Pathway in the Balloon-injured Rat Aorta. [PDF]

Physiol Res, 2021
Li Y, Guo J, Yu H, Liu X, Zhou J, Chu X, Xu Q, Sun T, Peng L, Yang X, Tang X.   +10 more
europepmc   +1 more source