Results 131 to 140 of about 24,420 (229)

Agonistic AT1 receptor autoantibodies and monocyte stimulation in hypertensive patients

, 2003
Background Agonistic AT1 receptor autoantibodies (AT1-AA) have been described in hypertensive and preeclamptic patients. Furthermore, monocytes are activated in hypertensive patients.
Homuth, V., Herberg, M., Doerffel, W., Doerffel, Y., Bochnig, N., Scholze, J., Chaoui, R., Wallukat, G., Pruss, A.   +8 more
core   +1 more source

Angiotensin II type-1 receptor autoantibodies and effects in neonates of women with preeclampsia

BMC Pregnancy and Childbirth
Background Maternal agonistic autoantibodies against the angiotensin II type 1 receptor (AT1-AAs) have been implicated in the pathophysiology of preeclampsia, but their presence in their offsprings and their possible neonatal effects have not been ...
Laure Ponthier, Chahrazed El Hamel, Perrine Coste Mazeau, Sophie Martinez, Sarah Wehbe, Rachel Froget, Catherine Yardin, Vincent Guigonis   +7 more
doaj   +1 more source

Stearoyl-CoA Desaturase (SCD) Induces Cardiac Dysfunction with Cardiac Lipid Overload and Angiotensin II AT1 Receptor Protein Up-Regulation. [PDF]

Int J Mol Sci, 2021
Abd Alla J, Jamous YF, Quitterer U.
europepmc   +1 more source

Angiotensin AT1 Receptor Blockade Protects the Brain from Ischemic Damage

, 2007
Angiotensin (Ang) AT1 receptors are considered to play an important role in ischemic stroke via degenerative processes leading to cell death. Recent clinical and basic studies show that systemic blockade of Ang AT1 receptors reduces brain lesion in ...
Penchikala, Madhuri
core  

Glucocorticoid Effects on the Programming of AT1b Angiotensin Receptor Gene Methylation and Expression in the Rat.

, 2010
Adverse events in pregnancy may 'programme' offspring for the later development of cardiovascular disease and hypertension. Previously, using a rodent model of programmed hypertension we have demonstrated the role of the renin-angiotensin system in this ...
Irina Bogdarina, Adrian J. L. Clark, Haase, A, Adrian J L Clark, Bogdarina, I, Andrea Haase, Clark, AJ, Haase Andrea, Langley-Evans Simon, Clark Adrian J. L., Bogdarina Irina, Irina Bogdarina, Simon Langley-Evans, Langley-Evans, S   +13 more
core   +1 more source

RAAS Blockade and COVID-19: Mechanistic Modeling of Mas and AT1 Receptor Occupancy as Indicators of Pro-Inflammatory and Anti-Inflammatory Balance. [PDF]

Clin Pharmacol Ther, 2021
Melissa Hallow K, Dave I.
europepmc   +1 more source

Mechanical stress and anionic lipids synergistically stabilize an atypical structure of the angiotensin II type 1 receptor (AT1).

PLoS Computational Biology
Environmental factors, including mechanical stress and surrounding lipids, can influence the response of GPCRs, such as the mechanosensitive angiotensin II type 1 receptor (AT1).
Rym Ben Boubaker, Daniel Henrion, Marie Chabbert   +2 more
doaj   +1 more source

Role of agonistic autoantibodies to the angiotensin II type 1 receptor (AT1-AA) in pathogenesis of preeclampsia

Global Medical Genetics
Preeclampsia(PE) is the most prevalent complication during pregnancy and constitutes a significant cause of morbidity and mortality among pregnant women and their fetuses. Recent studies have demonstrated elevated levels of angiotensin II type 1 receptor
Jing Wang, Lijuan Shan, Yanhui Zhao, Hongwen Cao, Shuhai Lan, Yizi Yan   +5 more
doaj   +1 more source

Interation between the protooncogene mas product and the angiotensin II AT1 receptor

, 2004
1. Em vista de evidencias de que o mas proto-oncogene pode modular as respostas do receptor AT1 a angiotensina II (AngII), o objetivo deste trabalho foi avaliar, por meio de tecnicas de biologia molecular e ensaios farmacologicos, a possivel interacao ...
Santos, Edson Lucas dos [UNIFESP]
core  

Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury. [PDF]

Cell Res, 2021
Fu Y, Huang Y, Yang Z, Chen Y, Zheng J, Mao C, Li Z, Liu Z, Yu B, Li T, Wang M, Xu C, Zhou Y, Zhao G, Jia Y, Guo W, Jia X, Zhang T, Li L, Liu Z, Guo S, Ma M, Zhang H, Liu B, Du J, Wang W, Tang C, Gao P, Xu Q, Wang X, Liu J, Sun J, Kong W.   +32 more
europepmc   +1 more source