Results 111 to 120 of about 24,420 (229)

Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) [PDF]

open access: yes, 2012
BACKGROUND: Laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) is a severe muscle-wasting disease for which no curative treatment is available.
Meinen, Sarina   +5 more
core   +1 more source

Parent‐adolescent relationships, COVID‐19‐related concerns, and life satisfaction among adolescents from diverse ethnic and socioeconomic backgrounds during school closures

open access: yesJournal of Research on Adolescence, Volume 36, Issue 2, June 2026.
Abstract Amidst the abrupt school closure due to the COVID‐19 pandemic, adolescents faced unexpected challenges. Drawing on data collected 1 week before, during, and 1 year after the first COVID‐19 school closure in Belgium, this study investigated (1) changes in life satisfaction, (2) whether parent–child relationship quality served as a protective ...
Jessie Hillekens   +2 more
wiley   +1 more source

Ang II-induced contraction is impaired in the aortas of renovascular hypertensive animal model

open access: yesVascular Biology
Renin–angiotensin system plays a critical role in blood pressure control, and the abnormal activation of the AT1 receptor contributes to the development of renovascular hypertension.
Bernah M Fahning   +4 more
doaj   +1 more source

Preeclampsia, Autoimmunity and The At1 Receptor

open access: yes, 2010
Preeclampsia (PE) is a disease of late pregnancy characterized by maternal hypertension and proteinuria. It is associated with preterm delivery and significant perinatal morbidity and mortality.
Irani, Roxanna A
core  

Chronic hypoxia upregulates the expression and function of AT1 receptor in rat carotid body

open access: yes, 2000
In the present study, the effects of chronic hypoxia on the expression and localization of angiotensin II (Ang II) receptors are investigated by semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) and by immunohistochemistry.
Lam, SY, Leung, PS, Fung, ML
core   +1 more source

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 353-364, June 2026.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon   +5 more
wiley   +1 more source

The AT1 Receptor Blocker Telmisartan Reduces Intestinal Mucus Thickness in Obese Mice. [PDF]

open access: yesFront Pharmacol, 2022
Nickel L   +9 more
europepmc   +1 more source

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 375-385, June 2026.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann   +2 more
wiley   +1 more source

Estrogen modulates AT1 receptor gene expression in vitro and in vivo

open access: yes, 1998
The AT1 receptor has been implicated in the pathogenesis of hypertension and atherosclerosis. Estrogen deficiency is also associated with cardiovascular diseases.
Strehlow, K.   +11 more
core  

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