Results 31 to 40 of about 13,112 (166)
AT1R Blockade and Treatment for Endometrial Cancer [PDF]
Clinical and Experimental Pharmacology, 2012 Copyright: © 2012 Bi FF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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AGT AND AT1R GENE POLYMORPHISM IN HYPERTENSIVE HEART DISEASE
International Journal of Clinical Practice, 2002 SUMMARYLeft ventricular hypertrophy in patients with hypertension is a main clinical prognostic entity. The aim of this study was to evaluate the association between mutations at genes of the renin‐angiotensin system (RAS) and the development of left ventricular hypertrophy.
M, Mettimano +5 more
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From mother to child--transplacental effect of AT1R-AAin preeclampsia [PDF]
Nephrology Dialysis Transplantation, 2010 Preeclampsia is a common hypertensive disorder of pregnancy and a leading cause of maternal and foetal morbidity and mortality worldwide. Preeclampsia requires the presence of the placenta and generally dramatically resolves after placental delivery.
Duska, Dragun, Aurélie, Philippe
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AT1R blockade in adverse milieus:role of SMRT and corepressor complexes
, 2015 ANG II type 1 receptor blockade (AT1R-BLK) is used extensively to slow down the progression of proteinuric kidney diseases. We hypothesized that AT1R-BLK provides podocyte protection through regulation of silencing mediator of retinoic acid and thyroid ...
Haque, Shabirul +31 more
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The FASEB Journal, 2021 Background Agonist‐induced AT1R Internalization, results from sequestration of the agonist‐receptor complex into “clathrin vesicles”, depending on the internalization proteins: β‐arrestin, clathrin. In this regard, we have shown that a 15,000 kDa polymer of Ang II (Ang II‐POL) at maximal concentration, upon a ...
Jesus Castillo‐Hernandez +3 more
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Endoplasmic reticulum stress increases AT1R mRNA expression via TIA-1-dependent mechanism
, 2016 As the formation of ribonucleoprotein complexes is a major mechanism of angiotensin II type 1 receptor (AT1R) regulation, we sought to identify novel AT1R mRNA binding proteins. By affinity purification and mass spectroscopy, we identified TIA-1.
Lehtonen, Jukka Y. A. +3 more
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Expression pattern of AT1R and AT2R in NSCs.
, 2013 A) Representative immunofluorescence images showing the AT1R expression in NSCs. 0D: 0 day; 3D: 3 days. NSCs cultured at day 0 or day 3 were fixed with 4% paraformaldehyde followed by immunostaining for nestin (red), a neural stem cell marker, and AT1R ...
Lie Gao (582562) +3 more
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, 2020 Hypertension, mediated by the Angiotensin II receptor type 1 (AT1R), is still the major cause of premature death despite the discovery of novel therapeutics, highlighting the importance of an in depth understanding of the drug-AT1R recognition mechanisms
Christina Papaemmanouil +5 more
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High fat diet activated Ang II-AT1R axis in rats.
, 2022 A. Protein expressions of kinases downstream of the Ang II-AT1R axis, p38 and ERK. B. Gene expression of Nox4 in adipose tissue. *p < 0.05 vs WT-ND rats. Data were presented as Mean ± S.E.M. n = 4.
Wenjuan Shi (3699118) +6 more
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Angiotensin II type-1 receptor (AT1R) regulates expansion, differentiation, and functional capacity of antigen-specific CD8+ T cells [PDF]
, 2016 Angiotensin II (Ang II) and its receptor AT1 (AT1R), an important effector axis of renin-angiotensin system (RAS), have been demonstrated to regulate T-cell responses.
Pinheiro, Ana Acacia Sá +2 more
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