Results 211 to 220 of about 186,580 (246)

On the identification of differentially-active transcription factors from ATAC-seq data. [PDF]

open access: yesPLoS Comput Biol
Gerbaldo FE   +7 more
europepmc   +1 more source

REnformer, a single-cell ATAC-seq predicting model to investigate open chromatin sites

open access: yes
Riva SG   +6 more
europepmc   +1 more source

Analytical Approaches for ATAC‐seq Data Analysis

open access: yesCurrent Protocols in Human Genetics, 2020
AbstractATAC‐seq, the assay for transposase‐accessible chromatin using sequencing, is a quick and efficient approach to investigating the chromatin accessibility landscape. Investigating chromatin accessibility has broad utility for answering many biological questions, such as mapping nucleosomes, identifying transcription factor binding sites, and ...
Jason P Smith, Nathan C Sheffield
exaly   +4 more sources

Bibliometric review of ATAC-Seq and its application in gene expression

open access: yesBriefings in Bioinformatics, 2022
Abstract With recent advances in high-throughput next-generation sequencing, it is possible to describe the regulation and expression of genes at multiple levels. An assay for transposase-accessible chromatin using sequencing (ATAC-seq), which uses Tn5 transposase to sequence protein-free binding regions of the genome, can be combined ...
Michael Gribskov   +2 more
exaly   +3 more sources

Measuring Chromatin Accessibility: ATAC-Seq

2021
Assay for Transposase-Accessible Chromatin using sequencing (ATAC-Seq) is a method to investigate the accessibility of chromatin in a genome-wide fashion. In this chapter, we provide a brief history of the chromatin accessibility field followed by a detailed protocol to perform ATAC-Seq assay.
Sahu, Sanjeeb Kumar   +2 more
openaire   +3 more sources

ATAC-Seq Optimization for Cancer Epigenetics Research

Journal of Visualized Experiments, 2022
The assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) probes deoxyribonucleic acid (DNA) accessibility using the hyperactive Tn5 transposase. Tn5 cuts and ligates adapters for high-throughput sequencing within accessible chromatin regions. In eukaryotic cells, genomic DNA is packaged into chromatin, a complex of DNA,
Mikhala, Cooper   +4 more
openaire   +2 more sources

ATAC-seq Data Processing

2023
ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) has gained wide popularity as a fast, straightforward, and efficient way of generating genome-wide maps of open chromatin and guiding identification of active regulatory elements and inference of DNA protein binding locations.
openaire   +2 more sources

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