Results 111 to 120 of about 18,950 (216)

Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes

Nature Communications, 2020
The ER is subject to autophagy (ER-phagy) for turnover, with Atg40 acting as a receptor to sequester ER with Atg8 in autophagosomes. Here, the authors show that Atg40 is clustered by interaction with Atg8 to generate local membrane curvature and promote ...
Keisuke Mochida, Akinori Yamasaki, Kazuaki Matoba, Hiromi Kirisako, Nobuo N. Noda, Hitoshi Nakatogawa   +5 more
doaj   +1 more source

Fungus Derived Indole‐3‐Acetic Acid Controls Developmental Conidial Death in Magnaporthe oryzae

Molecular Plant Pathology, Volume 27, Issue 4, April 2026.
The severity of rice blast disease, caused by the fungus Magnaporthe oryzae, is influenced by IAA concentration and cell density. IAA regulates ferroptotic death of the developing conidia by affecting iron and lipid homeostasis. ABSTRACT Ferroptotic death of the developing conidia is important for pathogenicity of the blast fungus Magnaporthe oryzae ...
Yuming Ma, Qiao Liu, Qing Shen, Ruhui Long, Xiaofang Xie, Lihong Dong, Zhibin Liang, Yi Zhen Deng   +7 more
wiley   +1 more source

In silico modeling of the Moniliophthora perniciosa Atg8 protein [PDF]

, 2013
Autophagy is defined as an intracellular system of lysosomal degradation in eukaryotic cells, and the genes involved in this process are conserved from yeast to humans.
Brendel, Martin, Cardoso, Thyago Hermylly Santana, Pereira, Alanna Cibelle Fernandes, Pungartnik, Cristina   +3 more
core   +2 more sources

Human ATG3 binding to lipid bilayers: role of lipid geometry, and electric charge [PDF]

, 2017
Specific protein-lipid interactions lead to a gradual recruitment of AuTophaGy-related (ATG) proteins to the nascent membrane during autophagosome (AP) formation.
Alonso Izquierdo, Alicia, Antón Helas, Zuriñe, Goñi Urcelay, Félix María, Hervás Hidalgo, Javier, Landajuela Larma, Ane, Shnyrova Zhadan, Anna   +5 more
core   +3 more sources

‘Candidatus Liberibacter Asiaticus’ Effector SECP8 Subverts Salicylic Acid‐Mediated Citrus Immunity via a Two‐Pronged Impairment of CsTCP15 Dimerization

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2335-2349, April 2026.
ABSTRACT Citrus Huanglongbing (HLB), a devastating disease caused by the unculturable bacterium ‘Candidatus Liberibacter asiaticus’ (CLas), poses a severe threat to global citrus production. CLas secretes effectors to suppress host immune responses and facilitate its colonisation. Previously, the CLas effector SECP8 (CLIBASIA_05330) has been identified
Mingyue Qin, Rongyu Pan, Yaqian Shi, Pan Shen, Yuanjian Qiu, Xuejin Cui, Xuefeng Wang, Changyong Zhou, Shimin Fu   +8 more
wiley   +1 more source

Autophagy is essential for mouse sense of balance [PDF]

, 2010
. This work was supported by grants from Ministerio de Ciencia e Innovación-Spain, Fundación “M. Botín,” the European Union (FP7 MicroEnviMet) and the NIH (grant DC008603 to Y.W. Lundberg).
Cabanillas Farpón, Rubén, Cabrera Benítez, María Sandra, Fernández Fernández, Álvaro, Fueyo Silva, Antonio Manuel, Germanà, Antonino, Lundberg, Yunxia W., López Otín, Carlos, Mariño García, Guillermo, Pérez Freije, José María, Rodríguez, Francisco, Salvador Montoliu, Natalia, Vega Álvarez, José Antonio   +11 more
core   +2 more sources

A Bacterial Effector Hijacks NBR1 to Modulate Both Autophagy and Ubiquitination‐Mediated Degradation That Promotes Bacterial Infection

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2492-2509, April 2026.
ABSTRACT Autophagy and the ubiquitin/26S proteasome system (UPS) play critical roles in the immune defence of the host against pathogen invasion. As a countermeasure, pathogens deploy effector proteins to subvert or hijack autophagy and UPS processes.
Yaqian Shi, Fang Fang, Xuejin Cui, Hongwei Shi, Zaiyu Yang, Xueyi Li, Changyong Zhou, Xuefeng Wang   +7 more
wiley   +1 more source

Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila [PDF]

, 2012
Autophagy delivers cytoplasmic material for lysosomal degradation in eukaryotic cells. Starvation induces high levels of autophagy to promote survival in the lack of nutrients. We compared genome-wide transcriptional profiles of fed and starved control,
Juhász, Gábor, Ménesi, Dalma, Nagy, Péter, Pircs, Karolina, Puskás, László G., Varga, Ágnes, Zvara, Ágnes, Érdi, Balázs   +7 more
core   +1 more source

No ATG8s, no problem? How LC3/GABARAP proteins contribute to autophagy [PDF]

Journal of Cell Biology, 2016
The ATG8 family LC3/GABARAP proteins are attached to the membrane of nascent autophagosomes, but their functions during autophagy are unclear. In this issue, Nguyen et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201607039) show that LC3/GABARAP proteins are not essential for autophagosome formation but are critical for autophagosome–lysosome ...
openaire   +3 more sources

Cloning and Expression Analysis of ATG8 (Autophagy-Related 8) Gene Family in Solanaceae

Plants
The autophagy-related gene family ATG8 (Autophagy-related 8) plays an important role in plant growth, development, and stress response. In this study, 15 ATG8 gene family sequences were amplified from Solanaceae, namely tobacco, tomato, and pepper, using
Yahan Chen, Yunshuang Lu, Shibo Dong, Chengde Yang, Shunyi Yang   +4 more
doaj   +1 more source