Results 71 to 80 of about 11,891 (170)
HY5 Positively Regulates Autophagy to Mediate Red Light‐Induced Tomato Fruit Ripening
ABSTRACT Red light accelerates tomato fruit ripening, but the molecular link between light signalling and autophagy remains unclear. Here, we show that red light promotes fruit coloration by activating autophagy in tomato pericarp. This response largely depends on the transcription factor HY5, which positively regulates this process by directly ...
Ye Guo +5 more
wiley +1 more source
ABSTRACT The anaphase‐promoting complex/cyclosome (APC/C) is a multi‐subunit E3 ubiquitin ligase that regulates cell cycle progression, but its role in plant‐pathogen interactions is poorly understood. Here, we demonstrate that regulation of the ubiquitin–proteasome system, involving APC/C‐associated components, is critical for coordinating host cell ...
Aline Köhn Carneiro +8 more
wiley +1 more source
Molecular insights and translational opportunities to enhance heat tolerance in rice
Abstract Heat stress is an increasingly serious threat to rice (Oryza sativa L.) productivity, yet the genetic and regulatory architecture underlying thermotolerance remain poorly resolved and fragmented across studies. Earlier research focused on individual pathways or specific developmental stages; however, recent advances now support an integrated ...
Prabhat Rana +7 more
wiley +1 more source
Coordination of Autophagosome–Lysosome Fusion by Atg8 Family Members [PDF]
Macroautophagy is a conserved intracellular lysosomal degradative pathway, vital for the maintenance of cellular homeostasis. It is characterized by double-membrane vesicles called autophagosomes, which sequester the cytoplasmic material destined for lysosomal turnover. In a final step, autophagosomes fuse with lysosomes to release their cargo into the
Kriegenburg, Franziska +2 more
openaire +3 more sources
Цель. Цель работы заключалась в исследовании взаимосвязи изменений уровней экспрессии генов кинезинов, потенциально вовлеченных в развитие стресс-индуцированной аутофагии у Arabidopsis thaliana с участием микротрубочек, и структурно-биологического ...
V. D. Olenieva +3 more
doaj +1 more source
Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
wiley +1 more source
Autophagy is an essential eukaryotic catabolic process through which damaged or superfluous cellular components are degraded and recycled via the formation of double-membrane autophagosomes.
Sung Un Huh
doaj +1 more source
Autophagy is a membrane-mediated degradation process, which is governed by sequential functions of Atg proteins. Although Atg proteins are highly conserved in eukaryotes, protozoa possess only a partial set of Atg proteins.
Kei Kitamura +7 more
doaj +1 more source
The ER is subject to autophagy (ER-phagy) for turnover, with Atg40 acting as a receptor to sequester ER with Atg8 in autophagosomes. Here, the authors show that Atg40 is clustered by interaction with Atg8 to generate local membrane curvature and promote ...
Keisuke Mochida +5 more
doaj +1 more source
Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo +4 more
wiley +1 more source

