Results 51 to 60 of about 18,950 (216)
N-terminal β-strand underpins biochemical specialization of an ATG8 isoform.
PLoS Biology, 2019 Autophagy-related protein 8 (ATG8) is a highly conserved ubiquitin-like protein that modulates autophagy pathways by binding autophagic membranes and a number of proteins, including cargo receptors and core autophagy components.
Erin K Zess +16 more
doaj +1 more source
Analysis of Autophagic Activity Using ATG8 Lipidation Assay in Arabidopsis thaliana
Bio-Protocol, 2018 As a fundamental metabolic pathway to degrade and recycle cellular cargos, autophagy is highly induced upon stress, starvation and senescence conditions in plants.
Mengqian Luo, Xiaohong Zhuang
doaj +1 more source
An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor [PDF]
, 2016 Plants use autophagy to safeguard against infectious diseases. However, how plant pathogens interfere with autophagy-related processes is unknown. Here, we show that PexRD54, an effector from the Irish potato famine pathogen Phytophthora infestans, binds
Altschul +48 more
core +2 more sources
Atg8-Family Proteins—Structural Features and Molecular Interactions in Autophagy and Beyond
Cells, 2020 Autophagy is a common name for a number of catabolic processes, which keep the cellular homeostasis by removing damaged and dysfunctional intracellular components.
Nicole Wesch +2 more
doaj +1 more source
The selectivity and specificity of autophagy in drosophila [PDF]
, 2012 Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou +27 more
core +2 more sources
, 2019 Autophagy depends on the E2 enzyme, Atg3, functioning in a conserved E1-E2-E3 trienzyme cascade that catalyzes lipidation of Atg8-family ubiquitin-like proteins (UBLs).
Grace, C. +5 more
core +1 more source
Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]
, 2018 The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin +3 more
core +1 more source
A role for Atg8–PE deconjugation in autophagosome biogenesis [PDF]
Autophagy, 2012 Formation of the autophagosome is likely the most complex step of macroautophagy, and indeed it is the morphological and functional hallmark of this process; accordingly, it is critical to understand the corresponding molecular mechanism. Atg8 is the only known autophagy-related (Atg) protein required for autophagosome formation that remains associated
Nair, Usha +7 more
openaire +3 more sources
Biological functions of the autophagy-related proteins Atg4 and Atg8 in Cryptococcus neoformans.
PLoS ONE, 2020 Autophagy is a mechanism responsible for intracellular degradation and recycling of macromolecules and organelles, essential for cell survival in adverse conditions.
Thiago Nunes Roberto +4 more
doaj +1 more source
Experimental Control and Characterization of Autophagy in Drosophila [PDF]
, 2008 Insects such as the fruit fly Drosophila melanogaster, which fundamentally reorganize their body plan during metamorphosis, make extensive use of autophagy for their normal development and physiology.
A.D. Velentzas +18 more
core +1 more source