Results 81 to 90 of about 18,950 (216)
Protein Science, Volume 35, Issue 5, May 2026.Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska +6 more
wiley +1 more source
For the last time, it is GFP-Atg8, not Atg8-GFP (and the same goes for LC3) [PDF]
Autophagy, 2011 GFP-Atg8/LC3 is a very useful marker to follow macroautophagy (hereafter autophagy). In contrast, Atg8/LC3-GFP has relatively limited uses. Unfortunately, many authors do not seem to appreciate the difference between these two constructs. I hope to put an end to that now.
openaire +2 more sources
ArabidopsisATG4 cysteine proteases specificity toward ATG8 substrates [PDF]
Autophagy, 2014 Macroautophagy (hereafter autophagy) is a regulated intracellular process during which cytoplasmic cargo engulfed by double-membrane autophagosomes is delivered to the vacuole or lysosome for degradation and recycling. Atg8 that is conjugated to phosphatidylethanolamine (PE) during autophagy plays an important role not only in autophagosome biogenesis ...
Park, Eunsook +2 more
openaire +4 more sources
Receptor proteins in selective autophagy [PDF]
, 2012 Autophagy has long been thought to be an essential but unselective bulk degradation pathway. However, increasing evidence suggests selective autophagosomal turnover of a broad range of substrates.
Behrends, Christian, Fulda, Simone
core +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT Wine yeasts play a central role in alcoholic fermentation and significantly contribute to the sensory attributes of wines through cellular autolysis during lees aging (sur lie), especially in white wines. This process releases organic compounds that alter the wine's chemical and sensory profile.
José Ricardo Machado dos Santos +1 more
wiley +1 more source
Aging Cell, Volume 25, Issue 5, May 2026.We developed a LASSO‐based approach to uncover a three‐layered “fan‐in fan‐out” network architecture for complex traits like yeast aging, showing that peripheral genes influence lifespan indirectly through master regulators, which converge on core functional modules (e.g., stress response, autophagy).
Meng Ma +12 more
wiley +1 more source
BMC Plant Biology, 2019 Background Autophagy is a conserved, highly-regulated catabolic process that plays important roles in growth, development and innate immunity in plants.
Mercy W. Macharia +4 more
doaj +1 more source
Autophagy processes are dependent on EGF receptor signaling [PDF]
, 2018 Autophagy is a not well-understood conserved mechanism activated during nutritional deprivation in order to maintain cellular homeostasis. In the present study, we investigated the correlations between autophagy, apoptosis and the MAPK pathways in ...
Capodifoglio, Sabrina +12 more
core +1 more source
Role of Autophagy in Glycogen Breakdown and Its Relevance to Chloroquine Myopathy [PDF]
, 2013 Several myopathies are associated with defects in autophagic and lysosomal degradation of glycogen, but it remains unclear how glycogen is targeted to the lysosome and what significance this process has for muscle cells.
Nieuwenhuis, Joppe +2 more
core +3 more sources
A Decline in Follicle Cell Function Is a Major Driver of Drosophila Ovarian Aging
Aging Cell, Volume 25, Issue 5, May 2026.Aging drives a progressive accumulation of defects in somatic follicle cells of the Drosophila ovary. These defects are accompanied by reduced tissue and genome integrity, altered transcriptional profiles, and disrupted germ‐soma coordination. Targeted overexpression of Atg8a in a subset of follicle cells mitigates these defects and preserves ...
Emily A. Wolfgram, Todd G. Nystul
wiley +1 more source