Results 151 to 160 of about 55,917 (264)

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3257-3264, September 2026.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo, Venceslas Bourdin, Abd El Kader Ait Tayeb, Sihem Benaboud, Inès Martins, Caroline Joyau, Myriam Benhamida, Isabelle Sermet‐Gaudelus, Clémence Martin, Pierre Régis Burgel, Céline Verstuyft, Laurent Chouchana, Estelle Ayme‐Dietrich   +12 more
wiley   +1 more source

Synchronous Duodenal and Pancreatic Metastases From Clear Cell Renal Cell Carcinoma 18 Years After Nephrectomy: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 63‐year‐old man presented with melena and severe anemia 18 years after nephrectomy for clear cell renal cell carcinoma. Imaging and biopsy confirmed duodenal and pancreatic metastases mimicking pancreaticobiliary malignancy. He underwent pancreaticoduodenectomy.
Ankit Kulkarni, Suhail Sapkota, Sai Sushrutha Mudupula Vemula, Shreya Motkur, Adarsh Jha, Rutwik Pradeep Sharma, Sumugdha Rayamajhi   +6 more
wiley   +1 more source

Development and In Vitro Evaluation of Atorvastatin and Rutin Co-Loaded Nanoliposomes for Enhanced Anti-Inflammatory and Cytotoxic Efficacy. [PDF]

Int J Mol Sci
Al-Samydai A, Kasabri V, Azzam H, Abu Hajleh MN, Moshawih S, Al Nsairat H, Al-Halaseh L, Banat H, Al-Zubaidy Z, Al-Tarawneh Z, Al-Hiari Y, El Khassawna T, Elstaty R, Abu AlSaman D, Al-Dujaili EAS.   +14 more
europepmc   +1 more source

4% 5‐Fluorouracil Cream for Actinic Keratoses: First Report of Efficacy and Tolerability in a Person Living With Human Immunodeficiency Virus Infection

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Actinic keratosis (AK) is a common premalignant skin condition associated with chronic ultraviolet exposure and an increased risk of progression to cutaneous squamous cell carcinoma (cSCC). Its prevalence rises with age and is influenced by multiple factors, including fair skin phototype and immunosuppression.
Gloria Hoxhallari, Aurelio Portincasa, Nicola Fini, Vincenzo Verdura, Liberato Roberto Cecchino, Fedele Lembo, Sergio Lo Caputo, Domenico Bonamonte, Caterina Foti, Francesco Drago, Giulia Ciccarese   +10 more
wiley   +1 more source

Spatial transcriptomics reveals atorvastatin modulates the tumor microenvironment to suppress breast cancer liver metastatic outgrowth. [PDF]

Neoplasia
Atale N, Chen J, Isett BR, Bao R, Meyer EM, Wells A.   +5 more
europepmc   +1 more source

Effect of loading dose of atorvastatin therapy prior to percutaneous coronary intervention in patients with acute coronary syndrome: a meta-analysis of six randomized controlled trials

, 2019
Mingfeng Ma,1,2 Lixia Bu,3 Li Shi,1 Renwei Guo,3 Bin Yang,2 Huili Cao,2 Liangping Luo,4 Ligong Lu5 1Department of Cardiology, Zhuhai Hospital Affiliated with Jinan University (Zhuhai People’s Hospital), Zhuhai, Guangdong 519000, People’s ...
Bu L, Lu L, Shi L, Cao H, Ma M, Luo L, Yang B, Guo R   +7 more
core  

Sintilimab Combined With Albumin‐Bound Paclitaxel and SOX Regimen as Conversion Therapy for Unresectable Advanced Gastric Cancer Achieving Complete Remission: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT For carefully selected patients with unresectable advanced gastric cancer, immunochemotherapy combining PD‐1 inhibitor with albumin‐bound paclitaxel and S‐1/oxaliplatin may achieve deep remission and enable successful R0 resection. Our findings suggest that this multimodal conversion approach could be considered in selected cases with ...
Yufan Tang, Boquan Zhou, Bingbing Wen, Ke Yu, Jiajia Jia, Ying Sha, Jixiang Liu, Luyao Li, Ruifang Fan   +8 more
wiley   +1 more source

Generic Versus Branded Atorvastatin: A Single-Center Comparative Analysis of Clinical Effectiveness and Post-Delisting Cost Savings in Saudi Arabia. [PDF]

Healthcare (Basel)
Jaafari AH, Al-Shwairkh AS, Alanazi MA, Alhammad AM, Alruthia Y.   +4 more
europepmc   +1 more source

Pancreatitis and Myocardial Infarction as Complications of Thrombotic Thrombocytopenic Purpura: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Thrombotic thrombocytopenic purpura (TTP) is a rare disease with a mortality rate of 90% if not treated promptly. Due to limited clinical experience and sometimes atypical presentation, early detection of TTP is not always easy. The pathophysiological mechanisms underlying TTP can accelerate thrombus formation and vascular occlusion ...
Farid Poursadegh, Motahhareh Karimoddini, Mohsen Seddigh‐shamsi, Najme Mohajer   +3 more
wiley   +1 more source

Combined Application of a Helix‐Fixation Leadless Pacemaker and a Subcutaneous Implantable Cardioverter‐Defibrillator in a Dialysis Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Combined use of S‐ICD and LP provides an effective alternative for patients requiring defibrillation and pacing while avoiding transvenous leads. This strategy is particularly valuable for patients with a high risk of infection, though careful consideration must be given to minimizing potential device–device interactions.
ZhaoWei Zhou, Wenbo Zhang, Jie Pang, Ying Zhou   +3 more
wiley   +1 more source