Atorvastatin Exerts Context-Dependent Metabolic and Beneficial Effects on Behavior and Apoptotic Signaling in a Cafeteria Diet-Induced Metabolic Dysfunction Model. [PDF]
Diogo ÍL +7 more
europepmc +1 more source
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy +7 more
wiley +1 more source
Lactoferrin and Nanotechnology: New Insights Into Glioblastoma Therapy
Current glioblastoma multiforme (GBM) management primarily relies on surgery, chemotherapy, and radiotherapy; however, therapeutic efficacy remains limited due to tumor invasiveness and restricted drug penetration across the blood–brain barrier. Lactoferrin (LF), an iron‐binding glycoprotein with receptor‐mediated transport capability, has emerged as a
Atena Abed, Javad Amini Mahabadi
wiley +1 more source
The impact of concomitant use of rosuvastatin or atorvastatin plus clopidogrel on the platelet inhibition and clinical outcomes in acute large-vessel minor stroke or TIA: A randomized controlled multi-center trial, the ROCATIS-1 trial. [PDF]
Zeinhom MG +22 more
europepmc +1 more source
Tryptophan metabolism modulates CRC via three microbiota‐regulated pathways with distinct dual‐mode effects. The kynurenine pathway provides biomarkers, serotonin pathway supports SSRI‐combined immunotherapy, indole pathway yields immunostimulatory metabolites, collectively offering translational prospects.
Ran Wang +5 more
wiley +1 more source
Comparative effects of atorvastatin and rosuvastatin on inflammatory biomarkers: a systematic review and meta-analysis of randomized head-to-head trials. [PDF]
Omayer A +8 more
europepmc +1 more source
Thermoresponsive Solid Dispersion to Enhance Dissolution Profile of Atorvastatin Calcium: An Industrially Sustainable Alternative to Conventional Approaches. [PDF]
Sherif AY, Ibrahim MA.
europepmc +1 more source
Mechanistic Dichotomy in Enantioselective Pd‐Catalyzed Alkylation of Pyrroles With Diazoesters
Ligand‐controlled mechanistic divergence controls the Pd‐catalyzed asymmetric alkylation of pyrroles with diazoesters. While bipyridine ligands promote a conventional metal‐carbene pathway, bipyridine‐N,N′‐dioxide ligands redirect catalysis through electrophilic CH metalation before carbene transfer.
Vladimir Yu. Vaganov +5 more
wiley +1 more source
Atorvastatin Mitigates Hypercholesterolemia-Induced Alterations in Cerebral Mitochondrial Dehydrogenases in Rats. [PDF]
Belczyk M +4 more
europepmc +1 more source
This graphical abstract highlights the versatile therapeutic potential and food applications of Terminalia arjuna, centering on its broad health‐promoting bioactivities. Key mechanisms described include adaptogenic, cardioprotective, gastroprotective, wound‐healing, and anti‐inflammatory effects mediated through Nrf2 and NF‐κB signaling pathways ...
Rameen Naeem +8 more
wiley +1 more source

