ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation,
Nawfal Hasan Siam +8 more
wiley +1 more source
Overcoming Drug Loading and Dosage Volume Challenges of Adsorption-Solidified SNEDDS by pH-Modulation Strategy: Atorvastatin Calcium and Glibenclamide as Model Drugs. [PDF]
Sherif AY, Altamimi MA.
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ABSTRACT Introduction Morganella morganii is an uncommon cause of urinary tract infection, typically associated with catheterization or underlying diseases. Case Presentation I report a rare case of severe hemorrhagic cystitis with massive intravesical clot retention in a 90‐year‐old woman without recent catheterization or diabetes mellitus ...
Yoshihiro Kawaguchi
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[<sup>18</sup>F]FDG PET/CT as an endpoint marker in drug interventional studies in atherosclerosis - a structured review. [PDF]
Gijsen CEW +4 more
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Bile acid metabolism and signaling in human and animal health: A One Health perspective
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
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Comparative Effects of Different Statin Regimens on Postoperative Outcomes in Isolated Coronary Artery Bypass Grafting: A Propensity Score-Matched Analysis. [PDF]
Beyazal OF +7 more
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We present the case of a 55‐year‐old male who experienced a cryptogenic ischemic stroke, likely due to a patent foramen ovale (PFO) in the setting of an incomplete cor triatriatum sinister (CTS) and a 30 mm GORE Cardioform Septal Occluder was successfully implanted.
Anastasios Apostolos +8 more
wiley +1 more source
The Role of 5-HT1A and 5-HT7 Receptors in Anxiety-like Behavior in Mice Treated with Subchronic Atorvastatin. [PDF]
Espinosa-Raya J +6 more
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Metabolism in Tumor: Mechanisms and Therapeutic Perspectives
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng +6 more
wiley +1 more source
Effect of loading dose atorvastatin on postoperative cardiovascular events in elderly patients with acute myocardial infarction undergoing percutaneous coronary intervention. [PDF]
Zhang L, Zhong F, Zhou C, Sun Y, Ye C.
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