Results 91 to 100 of about 1,971,906 (181)

The function of the ATP-binding cassette (ABC) transporter ABCB1 is not susceptible to actin disruption

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2013
Previously we have shown that the activity of the multidrug transporter ABCC1 (multidrug resistance protein 1), and its localization in lipid rafts, depends on cortical actin (Hummel I, Klappe K, Ercan C, Kok JW. Mol. Pharm. 2011 79, 229-40). Here we show that the efflux activity of the ATP-binding cassette (ABC) family member ABCB1 (P-glycoprotein ...
Meszaros, Peter, Hummel, Ina, Klappe, Karin, Draghiciu, Oana, Hoekstra, Dick, Kok, Jan W.   +5 more
openaire   +3 more sources

Genome-Wide Identification, Characterisation and Phylogenetic Analysis of 52 Striped Catfish (Pangasianodon hypophthalmus) ATP-Binding Cassette (ABC) Transporter Genes. [PDF]

Trop Life Sci Res, 2022
Lim LWK, Chung HH, Gan HM.
europepmc   +1 more source

Plant hormone transporters: what we know and what we would like to know

BMC Biology, 2017
Hormone transporters are crucial for plant hormone action, which is underlined by severe developmental and physiological impacts caused by their loss-of-function mutations.
Jiyoung Park, Youngsook Lee, Enrico Martinoia, Markus Geisler   +3 more
doaj   +1 more source

Genome-Wide Analysis of the ATP-Binding Cassette (ABC) Transporter Family in Zea mays L. and Its Response to Heavy Metal Stresses. [PDF]

Int J Mol Sci, 2022
Guo Z, Yuan X, Li L, Zeng M, Yang J, Tang H, Duan C.   +6 more
europepmc   +1 more source

Characterisation of the vibrio cholerae antibiotic resistance var operon [PDF]

, 2007
The discovery and use of antibiotics in the chemotherapy of bacterial infections has revolutionised medicine as it is today. Unfortunately, the progressive use of antibiotics has promoted the evolution of bacterial defences against these mediators and ...
Massam-Wu, Teresa
core  

Identification and Expression Characterization of ATP-Binding Cassette (ABC) Transporter Genes in Melon Fly. [PDF]

Insects, 2021
Xu HQ, Ma M, Ma YP, Zhang SY, Li WJ, Wei D, Wang JJ.   +6 more
europepmc   +1 more source

Maltose-binding protein effectively stabilizes the partially closed conformation of the ATP-binding cassette transporter MalFGK2

, 2017
Maltose transporter MalFGK2is a type-I importer in the ATP-binding cassette (ABC) transporter superfamily.
Gao, Xin, Huang, Xuhui, Xuhui Huang, Wenning Wang, Wang, Wenning, Weng, Jingwei, Jingwei Weng, Xin Gao, Gu, Shuo, Shuo Gu   +9 more
core   +1 more source

A Human ABCG2 SNP Variant, P269S (rs34678167, c.805C>T), Increases Cellular Resistance to Mitoxantrone and SN-38 Without Detectable Differences in ABCG2 Abundance in Total and Biotinylated Protein Fractions

Biomolecules
ABCG2 (BCRP/MXR) is an ATP-binding cassette transporter that plays a role in cellular resistance to various anticancer agents. While several non-synonymous single-nucleotide polymorphisms (SNPs) in the ABCG2 gene have been functionally characterized, the
Shiori Sato, Megumi Tsukamoto, Kayo Ozawa, Ritsuko Imai, Hiroshi Nakagawa   +4 more
doaj   +1 more source

PPAR Medicines and Human Disease: The ABCs of It All

PPAR Research, 2012
ATP-dependent binding cassette (ABC) transporters are a family of transmembrane proteins that pump a variety of hydrophobic compounds across cellular and subcellular barriers and are implicated in human diseases such as cancer and atherosclerosis ...
Anthony J. Apostoli, Christopher J. B. Nicol   +1 more
doaj   +1 more source

ABC transporter ABCA3 is expressed in acute myeloid leukemia blast cells and participates in vesicular transport

Haematologica, 2004
Drug resistance is a major issue in the treatment of acute myeloid leukemia (AML), and drug efflux by ATP-binding-cassette (ABC) transporters is one of the main mechanism involved in this resistance.
GG Wulf, S Modlich, N Inagaki, D Reinhardt, R Schroers, F Griesinger, L Trumper   +6 more
doaj