Results 31 to 40 of about 1,971,906 (181)

Solid-state NMR Reveals Asymmetric ATP hydrolysis in the Multidrug ABC Transporter BmrA [PDF]

, 2022
The detailed mechanism of ATP hydrolysis in ATP-binding cassette (ABC) transporters is still not fully understood. Here, we employed 31P solid-state NMR to probe the conformational changes and dynamics during the catalytic cycle by locking the multidrug ...
Denis, Lacabanne, Matthias, Ernst, Jean-Michel, Jault, Beat H., Meier, Anja, Böckmann, Margot, Di Cesare, Cédric, Orelle, Thomas, Wiegand, Cédric Orelle, Denis Lacabanne, Thomas Wiegand, Jean-Michel Jault, Margot Di Cesare, Anja Böckmann, Matthias Ernst, Beat H. Meier   +15 more
core   +2 more sources

Proteomic strategy for the analysis of the polychlorobiphenyl-degrading cyanobacterium Anabaena PD-1 exposed to Aroclor 1254.

PLoS ONE, 2014
The cyanobacterium Anabaena PD-1, which was originally isolated from polychlorobiphenyl (PCB)-contaminated paddy soils, has capabilities for dechlorinatin and for degrading the commercial PCB mixture Aroclor 1254.
Hangjun Zhang, Xiaojun Jiang, Wenfeng Xiao, Liping Lu   +3 more
doaj   +1 more source

Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance

Frontiers in Pharmacology, 2021
Multiple drug resistance (MDR), referring to the resistance of cancer cells to a broad spectrum of structurally and mechanistically unrelated drugs across membranes, severely impairs the response to chemotherapy and leads to chemotherapy failure ...
Huan Xiao, Yongcheng Zheng, Lingling Ma, Lili Tian, Qiu Sun   +4 more
doaj   +1 more source

Cardiac PET Imaging of ATP Binding Cassette (ABC) Transporters: Opportunities and Challenges

Pharmaceuticals, 2023
Adenosine triphosphate binding cassette (ABC) transporters are a broad family of membrane protein complexes that use energy to transport molecules across cells and/or intracellular organelle lipid membranes. Many drugs used to treat cardiac diseases have an affinity for these transporters.
Wanling Liu, Pascalle Mossel, Verena Schwach, Riemer H. J. A. Slart, Gert Luurtsema   +4 more
openaire   +5 more sources

ABC transporters and azole susceptibility in laboratory strains of the wheat pathogen Mycosphearella graminicola [PDF]

, 2002
Laboratory strains of Mycosphaerella graminicola with decreased susceptibilities to the azole antifungal agent cyproconazole showed a multidrug resistance phenotype by exhibiting cross-resistance to an unrelated chemical, cycloheximide or rhodamine 6G ...
Nistelrooy, J.G.M., Van, Zwiers, L.H., Stergiopoulos, I., Waard, M.A., De, Lute-harm Zwiers, Johannes G. M. Van Nistelrooy, Van Nistelrooy, Maarten A. De Waard, Johannes G. M, Ioannis Stergiopoulos   +9 more
core   +1 more source

ATP-binding cassette systems in Burkholderia pseudomallei and Burkholderia mallei. [PDF]

, 2007
© 2007 Harland et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Elie Dassa, Katherine A Brown, Brown Katherine A, Titball, Richard W, Helen S Atkins, Richard W Titball, Atkins Helen S, Brown, Katherine A, David N Harland, Dassa Elie, Harland, David N, Titball Richard W, Dassa, Elie, Harland David N, Atkins, Helen S   +14 more
core   +1 more source

ABC transporters in Dictyostelium discoideum development [PDF]

, 2013
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins.
Adam Kuspa, Gad Shaulsky (10030), Toplak Marko, Balaji Santhanam, Zhuchenko Olga, Adam Kuspa (45348), Marko Toplak, Gad Shaulsky, Shaulsky, Gad, Miranda Edward Roshan, Balaji Santhanam (155206), Zupan Blaz, Santhanam, Balaji, Kuspa Adam, Zupan, Blaz, Edward Roshan Miranda (446004), Marko Toplak (446006), Zhuchenko, Olga, Edward Roshan Miranda, Blaz Zupan (10031), Miranda, Edward Roshan, Olga Zhuchenko, Kuspa, Adam, Blaz Zupan, Olga Zhuchenko (446005), Santhanam Balaji, Shaulsky Gad, Toplak, Marko   +27 more
core   +2 more sources

ATP-BINDING CASSETTE TRANSPORTERS (ABC). NOMENCLATURE, STRUCTURE, MOLECULAR DIVERSITY, FUNCTION, CONTRIBUTION TO THE FUNCTIONING OF THE XENOBIOTICS TRANSFORMATION SYSTEM (А REWIEW)

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2020
ATP-binding cassette (ABC) transporters are membrane proteins responsible for removing various substrates from cells through cell membranes using the energy derived from ATP hydrolysis.
Lev Smirnov
doaj   +1 more source

Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and in HuH7 cells. [PDF]

, 2013
Signal transduction modulates expression and activity of cholesterol transporters. We recently demonstrated that the Ras/mitogen-activated protein kinase (MAPK) signaling cascade regulates protein stability of Scavenger Receptor BI (SR-BI) through ...
Enrich Bastús, Carles, Enrich Carlos, Karen Cecilia Chan, Monira Hoque, Darabi, Masoud, Reverter Martín, Meritxell, Hoque, Monira, Rentero Alfonso, Carles, Meritxell Reverter, Rentero Carles, Melanie Manetsch, Masoud Darabi, Mulay, Vishwaroop, Peta Wood, Grewal Thomas, Álvarez-Guaita, Anna, Heeren, Joerg, Anna Alvarez-Guaita, Kerry-Anne Rye, Darabi Masoud, Rye Kerry-Anne, Chan, Karen Cecilia, Manetsch, Melanie, Mulay Vishwaroop, Manetsch Melanie, Heeren Joerg, Carlos Enrich, Cairns, Rose, Reverter Meritxell, Joerg Heeren, Carles Rentero, Vishwaroop Mulay, Rose Cairns, Wood Peta, Wood, Peta, Grewal, Thomas, Rye, Kerry-Anne, Chan Karen Cecilia, Álvarez-Guaita Anna, Thomas Grewal, Hoque Monira, Cairns Rose   +41 more
core   +2 more sources

Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii

Nature Communications, 2017
The tripartite multidrug efflux pump MacA-MacB-TolC in Gram-negative bacterial pathogens is driven by the ATPase MacB, which belongs to the ATP-binding cassette (ABC) superfamily.
Ui Okada, Eiki Yamashita, Arthur Neuberger, Mayu Morimoto, Hendrik W. van Veen, Satoshi Murakami   +5 more
doaj   +1 more source