Results 11 to 20 of about 1,971,906 (181)

The human ATP-binding cassette (ABC) transporter superfamily [PDF]

Journal of Lipid Research, 2001
The transport of specific molecules across lipid membranes is an essential function of all living organisms and a large number of specific transporters have evolved to carry out this function.
Michael Dean, Yannick Hamon, Giovanna Chimini   +2 more
doaj   +5 more sources

Structural Features of the ATP-Binding Cassette (ABC) Transporter ABCA3. [PDF]

Int J Mol Sci, 2015
In this review we reported and discussed the structural features of the ATP-Binding Cassette (ABC) transporter ABCA3 and how the use of bioinformatics tools could help researchers to obtain a reliable structural model of this important transporter. In fact, a model of ABCA3 is still lacking and no crystallographic structures (of the transporter or of ...
Paolini A, Baldassarre A, Del Gaudio I, Masotti A.   +3 more
europepmc   +5 more sources

Human ATP-binding cassette (ABC) transporter family [PDF]

Human Genomics, 2009
There exist four fundamentally different classes of membrane-bound transport proteins: ion channels; transporters; aquaporins; and ATP-powered pumps. ATP-binding cassette (ABC) transporters are an example of ATP-dependent pumps.
Vasiliou Vasilis, Vasiliou Konstandinos, Nebert Daniel W   +2 more
doaj   +3 more sources

The ATP/Substrate Stoichiometry of the ATP-binding Cassette (ABC) Transporter OpuA [PDF]

Journal of Biological Chemistry, 2003
ATP-binding cassette (ABC) transport proteins catalyze the translocation of substrates at the expense of hydrolysis of ATP, but the actual ATP/substrate stoichiometry is still controversial. In the osmoregulated ABC transporter (OpuA) from Lactococcus lactis, ATP hydrolysis and substrate translocation are tightly coupled, and the activity of right-side-
Patzlaff, JS, Poolman, B, Patzlaff, Jason S.   +2 more
openaire   +5 more sources

Vanadate-catalyzed photocleavage of the signature motif of an ATP-binding cassette (ABC) transporter [PDF]

Proceedings of the National Academy of Sciences, 2002
The maltose transport complex of Escherichia coli , a member of the ATP-binding cassette (ABC) superfamily, is made up of two nucleotide-binding subunits, MalK 2 , which hydrolyze ATP with positive cooperativity, and two transmembrane subunits, MalF and
Erin E, Fetsch, Amy L, Davidson
openaire   +3 more sources

Screening of photosensitizers-ATP binding cassette (ABC) transporter interactions <i>in vitro</i>. [PDF]

Cancer Drug Resist
Aim: ATP-binding cassette (ABC) transporters are proteins responsible for the efflux of drug molecules from cancer cells, reducing the efficacy of anti-cancer treatments. This study assesses the susceptibility of a panel of clinically used photosensitizers to be transported by ABC transporters in vitro.
Vig S, Srivastava P, Rahman I, Jaranson R, Dasgupta A, Perttilä R, Uusimaa P, Huang HC.   +7 more
europepmc   +3 more sources

Mouse ATP-Binding Cassette (ABC) Transporters Conferring Multi-Drug Resistance

Anti-Cancer Agents in Medicinal Chemistry, 2015
The ABC (ATP-binding cassette) transporter is one of the largest and most ancient protein families with members functioning from protozoa to human. The resistance of cancer and tumor cells to anticancer drugs is due to the over-expression of some ABC transporters, which may finally lead to chemotherapy failure. The mouse ABC transporters are classified
L I, Shuaizhang, Wen, Zhang, Xuejiao, Yin, Shilai, Xing, Qunhui, Xie, Zhengyu, Cao, Bin, Zhao   +6 more
openaire   +4 more sources

The ATP-binding cassette (ABC) transporter OsABCG3 is essential for pollen development in rice. [PDF]

Rice (N Y), 2018
The pollen wall, which protects male gametophyte against various stresses and facilitates pollination, is essential for successful reproduction in flowering plants. The pollen wall consists of gametophyte-derived intine and sporophyte-derived exine. From outside to inside of exine are tectum, bacula, nexine I and nexine II layers.
Chang Z, Jin M, Yan W, Chen H, Qiu S, Fu S, Xia J, Liu Y, Chen Z, Wu J, Tang X.   +10 more
europepmc   +5 more sources

Twenty years of ATP-binding cassette (ABC) transporters [PDF]

Pflügers Archiv - European Journal of Physiology, 2006
ATP-binding cassette (ABC) transporters constitute a large superfamily of primary active transport systems, which play a diversity of physiological roles, and are found in all cells of all kingdoms [3]. The year 2006 marks the 20th anniversary of the identification of this superfamily of proteins in 1986 [4].
Stieger, Bruno, Higgins, Christopher F
openaire   +2 more sources

Transport and catabolism of murein tripeptide in Escherichia coli K-12 [PDF]

, 2011
In bacteria, extracellular peptides are not only a source of nutrients but also play important roles in cell-cell communication. The primary mode of uptake of these peptides in bacteria is via ATP Binding Cassette (ABC) transporters.
Maqbool, Abbas
core   +4 more sources