Results 11 to 20 of about 3,142,470 (292)
Membrane trafficking of ATP-sensitive potassium channels [PDF]
, 2005 ATP-sensitive potassium (KATp) channels are known to play a vital role in the regulation of insulin secretion from pancreatic 0-cells. Changes in the ratio of [ATP]/[ADP] within the cell are known to regulate the activity of channels, but very little is ...
Smith, Andrew James
core +7 more sources
Pharmacogenomics and Personalized Medicine, 2010 Veronica Lang, Peter E LightDepartment of Pharmacology and Alberta Diabetes Institute, Faculty of Medicine and Dentistry, School of Molecular and Systems Medicine, University of Alberta, Edmonton, Alberta, CanadaAbstract: Neonatal diabetes mellitus (NDM)
Veronica Lang, Peter E Light
doaj +1 more source
The role of potassium channels and calcium in the relaxation mechanism of magnesium sulfate on the isolated rat uterus [PDF]
Archives of Biological Sciences, 2019 MgSO4 is used as a tocolytic agent. It is considered to be a calcium channel antagonist, but a different mechanism of its action might be involved. The aim of this study was to examine the contribution of calcium concentrations and potassium channels in ...
Sokolović Dragana +6 more
doaj +1 more source
Mitochondria from rat uterine smooth muscle possess ATP-sensitive potassium channel [PDF]
Saudi Journal of Biological Sciences, 2018 Vadzyuk OB, Kosterin SO.
exaly +2 more sources
Pulmonary vasoconstrictor action of KCNQ potassium channel blockers [PDF]
, 2006 KCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important physiological functions. Recent reports indicate that KCNQ channels may also be expressed in portal vein where they are suggested to influence ...
Joshi, Shreena +2 more
core +5 more sources
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects
Frontiers in Pharmacology, 2022 Bisphosphonates (BPs) are the most used bone-specific anti-resorptive agents, often chosen as first-line therapy in several bone diseases characterized by an imbalance between osteoblast-mediated bone production and osteoclast-mediated bone resorption ...
Rosa Scala +11 more
doaj +1 more source
ATP-sensitive potassium channels and vascular function [PDF]
Channels, 2015 ATP-sensitive potassium channels (KATP) are widely distributed in different organs of the body. They are best described in pancreatic β cells and cardiac myocytes but are also present in the periph...
Qadeer, Aziz, Yiwen, Li, Andrew, Tinker
openaire +2 more sources
Ion Channel Dysfunction in Astrocytes in Neurodegenerative Diseases
Frontiers in Physiology, 2022 Astrocytes play an important role in the central nervous system (CNS). Ion channels in these cells not only function in ion transport, and maintain water/ion metabolism homeostasis, but also participate in physiological processes of neurons and glial ...
Sijian Wang +5 more
doaj +1 more source
Structure of a Pancreatic ATP-Sensitive Potassium Channel [PDF]
Cell, 2017 ATP-sensitive potassium channels (KATP) couple intracellular ATP levels with membrane excitability. These channels play crucial roles in many essential physiological processes and have been implicated extensively in a spectrum of metabolic diseases and disorders.
Ningning, Li +5 more
openaire +2 more sources
Diazoxide affects mitochondrial bioenergetics by the opening of mKATP channel on submicromolar scale
BMC Molecular and Cell Biology, 2020 Background Cytoprotection afforded by mitochondrial ATP-sensitive K+-channel (mKATP-channel) opener diazoxide (DZ) largely depends on the activation of potassium cycle with eventual modulation of mitochondrial functions and ROS production.
Olga Akopova +4 more
doaj +1 more source