Results 91 to 100 of about 45,380 (194)

Sodium butyrate activates the KATP channels to regulate the mechanism of Parkinson's disease microglia model inflammation

Immunity, Inflammation and Disease
Background Parkinson's disease (PD) is a common neurodegenerative disorder. Microglia‐mediated neuroinflammation has emerged as an involving mechanism at the initiation and development of PD. Activation of adenosine triphosphate (ATP)‐sensitive potassium
Ye Xu, Laofu Wen, Yunyi Tang, Zhenqiang Zhao, Miaojing Xu, Tan Wang, Zhibin Chen   +6 more
doaj   +1 more source

High level production, characterization and structural analysis of neuronal calcium-activated potassium channels

, 2004
Kaliumkanäle vermitteln als reguliertes Porenprotein den selektiven Transport von Kaliumionen durch die Zellmembran. Sie sind für physiologische Prozesse wie Neurosekretion und Tonus der glatten Muskulatur von Bedeutung.
Licata, Luana, Licata, L.
core  

A novel hydrogen sulfide donor reduces neuroinflammation and seizures by activating ATP-sensitive potassium channels

Neuroscience Research
Epilepsy is a common neurological disorder worldwide. Hydrogen sulfide (H2S) has been found to have anti-seizure effects. However, its mechanism remains to be explored.
Qiyun Kang, Ziting Zhu, Zhongrui Liu, Fei Li, Yan He, Yaru Yang, Xutao Wang, Shuisheng Lei, Zishu Yuan, Xiaoqin Zhu   +9 more
doaj   +1 more source

Antinociceptive effect of Nephelium lappaceum L. fruit peel and the participation of nitric oxide, opioid receptors, and ATP-sensitive potassium channels. [PDF]

Front Pharmacol, 2023
Oliveira AS, Biano LS, Palmeira DN, de Almeida DR, Lopes-Ferreira M, Kohlhoff M, Sousa JAC, Brandão GC, Silva AMOE, Grespan R, Camargo EA.   +10 more
europepmc   +1 more source

Efeitos da agmatina em modelos animais de depressão e mania [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Mood disorders are chronic and severe mental disorders.
Budni, Josiane
core  

ATP-sensitive potassium channels in zebrafish cardiac and vascular smooth muscle. [PDF]

J Physiol, 2022
Singareddy SS, Roessler HI, McClenaghan C, Ikle JM, Tryon RC, van Haaften G, Nichols CG.   +6 more
europepmc   +1 more source

ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm? [PDF]

Diabetes, 2022
Nichols CG, York NW, Remedi MS.
europepmc   +1 more source

The Antiallodynic Action Target of Intrathecal Gabapentin: Ca2+ Channels, K-Atp Channels or N-Methyl-D-Aspartic Acid Receptors?

, 2009
Gabapentin is a novel analgesic whose mechanism of action is not known. We investigated in a postoperative pain model whether adenosine triphosphate (ATP)sensitive K+ (K-ATP) channels, N-methyl-D-aspartic acid (NMDA) receptors, and Ca2 + channels are ...
鄭仁坤;邱麗珠, CHENG, JEN-KUN;CHIOU, LIH-CHU   +1 more
core  

Mitochondrial Dysfunction and Ion Imbalance in a Rat Model of Hemodialysis-Induced Myocardial Stunning

Biomedicines
Background/Objectives: Hemodialysis-induced myocardial stunning (HIMS) is a frequent complication in patients undergoing maintenance hemodialysis, characterized by transient left ventricular dysfunction due to ischemic episodes. Mitochondrial dysfunction
Yuxin Nie, Liyu Lin, Qiang Yang, Jiachang Hu, Minmin Sun, Fangfang Xiang, Xuesen Cao, Jinbo Yu, Yaqiong Wang, Jie Teng, Xiaoqiang Ding, Bo Shen, Zhen Zhang   +12 more
doaj   +1 more source

Omega-3 polyunsaturated fatty acid-induced vasodilation in mouse aorta and mesenteric arteries is not mediated by ATP-sensitive potassium channels. [PDF]

Front Physiol, 2022
Bercea C, Limbu R, Behnam K, Ng KE, Aziz Q, Tinker A, Tamagnini F, Cottrell GS, McNeish AJ.   +8 more
europepmc   +1 more source