Results 71 to 80 of about 45,380 (194)
KATP channels and cardioprotection [PDF]
Arhiv za farmacijuThis review discusses ATP-sensitive potassium (KATP) channels, which connect intracellular energy metabolism to cellular electrical activity and play crucial roles in various physiological processes, particularly in the pancreas and cardiovascular system.
Taskin Eylem +5 more
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Trimethylamine N-oxide (TMAO) acutely alters ionic currents but does not increase cardiac cell death
Frontiers in PhysiologyBackgroundTrimethylamine N-oxide (TMAO) is a product of the action of gut microbiota on choline and other choline-containing compounds ingested in the diet.
Simona Esposito +5 more
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Structure and function of potassium and calcium channels [PDF]
, 2005 In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
core
Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats
The Scientific World Journal, 2012 This paper shows a new finding about the decrease of relaxative response to loperamide in prostate of spontaneously hypertensive rats (SHR) as compare to normal rats (WKY).
Liang-Ming Lee +3 more
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ATP-Sensitive Potassium Channels: Structures, Functions, and Pathophysiology
The Japanese Journal of Physiology, 1998 ATP-sensitive potassium channels (KATP channels) play important roles in various tissues by coupling cell metabolic status to electrical activity. Recently, molecular biological and electrophysiological techniques have revealed the molecular basis of the KATP channels to be a complex of the Kir6.0 subunit, a member of the inwardly rectifying K+ channel
INAGAKI, Nobuya, SEINO, Susumu
openaire +3 more sources
Study of a glycine hinge in ATP-sensitive potassium channels
, 2023 Potassium channels regulate cell excitability by gating K⁺ flux through transmembrane pores. Inward rectifier (Kir) channels, including ATP-sensitive K⁺ (KATP) channels, rely on TM2 flexibility for gating, hypothesized to involve a glycine hinge.
Bushman, Jeremy
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ATP-sensitive potassium channels in smooth muscle cells from guinea pig urinary bladder
, 1993 We explored the possibility that ATP-sensitive potassium (K(ATP)) channels exist in urinary bladder smooth muscle, since synthetic openers (e.g., lemakalim) of K(ATP) channels in other tissues relax bladder smooth muscle.
Bonev, A. D. +3 more
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, 2012 Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Szalontai, B. +23 more
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The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines.
, 2000 The pharmacology of hSK1, a small conductance calcium-activated potassium channel, was studied in mammalian cell lines (HEK293 and COS-7). In these cell types, hSK1 forms an apamin-sensitive channel with an IC(50) for apamin of 8 nM in HEK293 cells and ...
Shah, M, Haylett, DG
core
, 2020 OBJECTIVE: Chondrocytes are highly sensitive to variations in extracellular glucose and oxygen levels in the extracellular matrix. As such, they must possess a number of mechanisms to detect and respond to alterations in the metabolic state of cartilage.
Gent, TC +5 more
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