Results 1 to 10 of about 321,813 (142)

Diacylglycerol Signaling Underlies Astrocytic ATP Release [PDF]

Neural Plasticity, 2011
Astrocytes have the ability to modulate neuronal excitability and synaptic transmission by the release of gliotransmitters. The importance of ATP released downstream of the activation of Gq-coupled receptors has been well established, but the mechanisms ...
Alison E. Mungenast
doaj   +3 more sources

Learning the ABCs of ATP release. [PDF]

J Biol Chem, 2020
ATP plays important roles outside the cell, but the mechanism by which it is arrives in the extracellular environment is not clear. Dunn et al now show that decreases in cellular cholesterol levels mediated by the ABCG1 transporter increase ATP release by volume-regulated anion channels under hypotonic conditions.
Libby AE, Jones B, Levi M.
europepmc   +3 more sources

Ingredients of Vicks VapoRub inhibit rhinovirus-induced ATP release [PDF]

Drugs in Context, 2023
Background: Over-the-counter therapies, such as Vicks VapoRub, are frequently used in the management of upper respiratory tract infection symptoms.
Rebecca J Stinson, Alyn H Morice, Basir Ahmad, Laura R Sadofsky   +3 more
doaj   +2 more sources

Mathematical model for promotion of wound closure with ATP release [PDF]

Biophysics and Physicobiology, 2023
To computationally investigate the recent experimental finding such that extracellular ATP release caused by exogeneous mechanical forces promote wound closure, we introduce a mathematical model, the Cellular Potts Model (CPM), which is a popular ...
Kenta Odagiri, Hiroshi Fujisaki, Hiroya Takada, Rei Ogawa   +3 more
doaj   +2 more sources

Hypoxia induces robust ATP release from erythrocytes in ApoE-LDLR double-deficient mice [PDF]

Frontiers in Physiology
Red blood cells (RBCs) play a role in the regulation of vascular tone via release of adenosine triphosphate (ATP) into the vasculature in response to various stimuli.
Fatih Celal Alcicek, Fatih Celal Alcicek, Jakub Dybas, Katarzyna Bulat, Tasnim Mohaissen, Tasnim Mohaissen, Ewa Szczesny-Malysiak, Magdalena Franczyk-Zarow, Katarzyna M. Marzec   +8 more
doaj   +2 more sources

ATP release mediated by TRPM3 enhances invasion in glioblastoma [PDF]

Animal Cells and Systems
Glioblastoma (GBM) is the most aggressive and lethal form of primary brain tumor, characterized by uncontrolled proliferation and invasion into surrounding brain tissue.
Kkot Garam Bae, Chae Won Song, Jae Hong Yoo, Myunghoon Lee, Noah Koo, Gangsan Lee, Yongmin Mason Park, Jihwan Yoo, In-Young Hwang, Dong Ho Woo, C. Justin Lee, Kyung-Seok Han   +11 more
doaj   +2 more sources

TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells [PDF]

Respiratory Research
Repetitive bouts of coughing expose the large airways to significant cycles of shear stress. This leads to the release of alarmins and the tussive agent adenosine triphosphate (ATP) which may be modulated by the activity of ion channels present in the ...
Orla M. Dunne, S. Lorraine Martin, Gerard P. Sergeant, Daniel F. McAuley, Cecilia M. O’Kane, Brian Button, Lorcan P. McGarvey, Fionnuala T. Lundy   +7 more
doaj   +2 more sources

ATP Release Drives Inflammation with Lysophosphatidylcholine [PDF]

ImmunoHorizons, 2020
Abstract Lysophosphatidylcholine (LPC), a dominant lipid component of oxidized low-density lipoprotein, plays a major role in inflammation associated with atherosclerosis and neurodegenerative disorders. It activates inflammatory responses from macrophages, neuronal cells, and endothelial cells.
Sana, Ismaeel, Ayub, Qadri
openaire   +3 more sources

Mitochondria regulate TRPV4‐mediated release of ATP [PDF]

British Journal of Pharmacology, 2021
Background and PurposeCa2+influx via TRPV4 channels triggers Ca2+release from the IP3‐sensitive internal store to generate repetitive oscillations. Although mitochondria are acknowledged regulators of IP3‐mediated Ca2+release, how TRPV4‐mediated Ca2+signals are regulated by mitochondria is unknown.
Xun Zhang, Matthew D. Lee, Charlotte Buckley, Calum Wilson, John G. McCarron   +4 more
openaire   +4 more sources

ATP‐induced ATP release from astrocytes [PDF]

Journal of Neurochemistry, 2003
AbstractPropagation of interastrocyte Ca2+waves is mediated by diffusion of extracellular adenosine triphosphate (ATP), and may require regenerative release of ATP. The ability of ATP to initiate release of intracellular ATP was assessed by labeling adenine nucleotide pools in astrocyte cultures with14C‐adenine.
Christopher M, Anderson, Jennifer P, Bergher, Raymond A, Swanson   +2 more
openaire   +2 more sources