Results 1 to 10 of about 837,065 (393)
An overview of ATP synthase, inhibitors, and their toxicity [PDF]
Heliyon, 2023 Mitochondrial complex V (ATP synthase) is a remarkable molecular motor crucial in generating ATP and sustaining mitochondrial function. Its importance in cellular metabolism cannot be overstated, as malfunction of ATP synthase has been linked to various ...
Arwa R. Althaher, Mohammad Alwahsh
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ATP Synthase: Structure, Function and Inhibition [PDF]
Biomolecular Concepts, 2019 Oxidative phosphorylation is carried out by five complexes, which are the sites for electron transport and ATP synthesis. Among those, Complex V (also known as the F1F0 ATP Synthase or ATPase) is responsible for the generation of ATP through ...
Neupane Prashant +3 more
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Inhibitors of ATP Synthase as New Antibacterial Candidates
Antibiotics, 2023 ATP, the power of all cellular functions, is constantly used and produced by cells. The enzyme called ATP synthase is the energy factory in all cells, which produces ATP by adding inorganic phosphate (Pi) to ADP.
Rawan Mackieh +5 more
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The ATP Synthase Deficiency in Human Diseases [PDF]
Life, 2021 Human diseases range from gene-associated to gene-non-associated disorders, including age-related diseases, neurodegenerative, neuromuscular, cardiovascular, diabetic diseases, neurocognitive disorders and cancer. Mitochondria participate to the cascades
Chiara Galber +3 more
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Mitochondrial ATP Synthase is a Target of Oxidative Stress in Neurodegenerative Diseases
Frontiers in Molecular Biosciences, 2022 The mitochondrial ATP synthase is responsible for the production of cellular ATP, and it does so by harnessing the membrane potential of the mitochondria that is produced by the sequential oxidation of select cellular metabolites.
Brad Ebanks +2 more
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ATP Synthase Abundance in Neuronal Extracellular Vesicles Reflects Changes in the Mitochondria of Parent Neurons [PDF]
Journal of Extracellular VesiclesMitochondrial proteins are found in extracellular vesicles (EVs) such as neuron‐derived EVs (NEVs). Yet whether and how NEV‐borne mitochondrial proteins relate to the state of mitochondria in the parent neurons is unclear.
Pamela J. Yao +3 more
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Structure of the human ATP synthase.
Molecular Cell, 2023 Biological energy currency ATP is produced by F1Fo-ATP synthase. However, the molecular mechanism for human ATP synthase action remains unknown. Here, we present snapshot images for three main rotational states and one substate of human ATP synthase using cryoelectron microscopy. These structures reveal that the release of ADP occurs when the β subunit
Yuezheng Lai +15 more
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Subtomogram averages of mitochondrial ATP synthase dimers from plants show a conserved extra density at the peripheral stalk [PDF]
IUCrJWe analyzed ATP synthase dimers in mitochondria purified from four plant species by subtomogram averaging, using Saccharomyces cerevisiae as a control.
Thorsten B. Blum +2 more
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ATP Synthase Members of Chloroplasts and Mitochondria in Rubber Trees (Hevea brasiliensis) Response to Plant Hormones [PDF]
PlantsATP synthase is a key enzyme in photophosphorylation in photosynthesis and oxidative phosphorylation in respiration, which can catalyze the synthesis of ATP and supply energy to organisms. ATP synthase has been well studied in many animal species but has
Bingbing Guo +5 more
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Structure of a bacterial ATP synthase
eLife, 2018 ATP synthases produce ATP from ADP and inorganic phosphate with energy from a transmembrane proton motive force. Bacterial ATP synthases have been studied extensively because they are the simplest form of the enzyme and because of the relative ease of ...
Hui Guo, Toshiharu Suzuki, J. Rubinstein
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