Results 11 to 20 of about 329,086 (345)

Sequential Immune Acquisition of Monoclonal Antibodies Enhances Phagocytosis of Acinetobacter baumannii by Recognizing ATP Synthase. [PDF]

Vaccines (Basel)
Huang D, Zeng Z, Li Z, Li M, Zhai L, Lin Y, Xu R, Qu J, Zhang B, Zhao W, Shen C.   +10 more
europepmc   +2 more sources

ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast

Scientific Reports, 2023
The mitochondrial ATP synthase, an enzyme that synthesizes ATP and is involved in the formation of the mitochondrial mega-channel and permeability transition, is a multi-subunit complex. In S.
Chiranjit Panja, Aneta Wiesyk, Katarzyna Niedźwiecka, Emilia Baranowska, Roza Kucharczyk   +4 more
doaj   +1 more source

Inhibitors of ATP Synthase as New Antibacterial Candidates

Antibiotics, 2023
ATP, the power of all cellular functions, is constantly used and produced by cells. The enzyme called ATP synthase is the energy factory in all cells, which produces ATP by adding inorganic phosphate (Pi) to ADP.
Rawan Mackieh, Nadia Al-Bakkar, Milena Kfoury, Rabih Roufayel, Jean-Marc Sabatier, Ziad Fajloun   +5 more
doaj   +1 more source

Defueling the cancer: ATP synthase as an emerging target in cancer therapy

Molecular Therapy: Oncolytics, 2021
Reprogramming of cellular metabolism is a hallmark of cancer. Mitochondrial ATP synthase (MAS) produces most of the ATP that drives the cell. High expression of the MAS-composing proteins is found during cancer and is linked to a poor prognosis in ...
Ting Wang, Fei Ma, Hai-li Qian
doaj   +1 more source

Human F1F0 ATP synthase, mitochondrial ultrastructure and OXPHOS impairment: a (super-)complex matter? [PDF]

PLoS ONE, 2013
Mitochondrial morphogenesis is a key process of cell physiology. It is essential for the proper function of this double membrane-delimited organelle, as it ensures the packing of the inner membrane in a very ordered pattern called cristae.
Johann Habersetzer, Isabelle Larrieu, Muriel Priault, Bénédicte Salin, Rodrigue Rossignol, Daniel Brèthes, Patrick Paumard   +6 more
doaj   +1 more source

Mitochondrial F-ATP Synthase Co-Migrating Proteins and Ca²⁺-Dependent Formation of Large Channels

Cells, 2023
Monomers, dimers, and individual FOF1-ATP synthase subunits are, presumably, involved in the formation of the mitochondrial permeability transition pore (PTP), whose molecular structure, however, is still unknown.
Anna B. Nikiforova, Yulia L. Baburina, Marina P. Borisova, Alexey K. Surin, Ekaterina S. Kharechkina, Olga V. Krestinina, Maria Y. Suvorina, Svetlana A. Kruglova, Alexey G. Kruglov   +8 more
doaj   +1 more source

Reversible Thiol Oxidation Inhibits the Mitochondrial ATP Synthase in Xenopus Laevis Oocytes

Antioxidants, 2020
Oocytes are postulated to repress the proton pumps (e.g., complex IV) and ATP synthase to safeguard mitochondrial DNA homoplasmy by curtailing superoxide production. Whether the ATP synthase is inhibited is, however, unknown.
James Cobley, Anna Noble, Rachel Bessell, Matthew Guille, Holger Husi   +4 more
doaj   +1 more source

ATP synthase-associated coiled-coil-helix-coiled-coil-helix (CHCH) domain-containing proteins are critical for mitochondrial function in Toxoplasma gondii

mBio, 2023
Coiled-coil-helix-coiled-coil-helix (CHCH) domains consist of two pairs of cysteine residues that are oxidized to form disulfide bonds upon mitochondrial import.
Madelaine M. Usey, Diego Huet
doaj   +1 more source

¹⁷⁷Lu Anti-Angiogenic Radioimmunotherapy Targeting ATP Synthase in Gastric Cancer Model. [PDF]

Antibodies (Basel)
Park BN, An YS, Kim SM, Lee SJ, Park YJ, Yoon JK.   +5 more
europepmc   +3 more sources

ATP synthase [PDF]

EMBO reports, 2000
All living species use ATP as a general source of energy by hydrolysing it into ADP and phosphate. In most species the regeneration of this vital molecule is catalysed by the H+-transporting F1F0 ATP synthases, marvellous machines that couple the flow of protons down an electrochemical gradient to form ATP from ADP and phosphate.
openaire   +2 more sources