Results 11 to 20 of about 99,033 (266)

ATR phosphoproteomics

open access: yes, 2023
R scripts used in the publication for the analysis of the phospho-proteomics dataset.
Jadav, Rathan S   +2 more
  +7 more sources

Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA [PDF]

open access: yesNature Communications, 2018
AbstractATR kinase is activated by RPA-coated single-stranded DNA (ssDNA) to orchestrate DNA damage responses. Here we show that ATR inhibition differs from ATR loss. Mouse model expressing kinase-dead ATR (Atr+/KD), but not loss of ATR (Atr+/−), displays ssDNA-dependent defects at the non-homologous region of X-Y chromosomes during male meiosis ...
Demis Menolfi   +8 more
openaire   +3 more sources

Structural and strategic landscape of PIKK protein family and their inhibitors: an overview

open access: yesFrontiers in Bioscience-Landmark, 2020
Phosphatidylinositol-3 kinase-related kinases (PIKKs) is a class of six unique serine/threonine kinases that are characterized as high molecular mass colossal proteins present in multicellular organisms.
Deekshi Angira   +2 more
doaj   +1 more source

BrainLiner: A Neuroinformatics Platform for Sharing Time-Aligned Brain-Behavior Data

open access: yesFrontiers in Neuroinformatics, 2016
Data-driven neuroscience aims to find statistical relationships between brain activity and task behavior from large-scale datasets. To facilitate high-throughput data processing and modeling, we created BrainLiner as a web platform for sharing time ...
Makoto eTakemiya   +4 more
doaj   +1 more source

Genotoxic stress signalling as a driver of macrophage diversity

open access: yesCell Stress, 2022
Tissue macrophages arise from yolk sac, fetal liver and hemato-poietic progenitors and adopt diverse transcriptional programs and phenotypes, instructed by their microenvironment.
Ana Kasapi, Antigoni Triantafyllopoulou
doaj   +1 more source

Discriminative sparsity for Sonar ATR [PDF]

open access: yesOCEANS 2015 - MTS/IEEE Washington, 2015
Advancements in Sonar image capture have enabled researchers to apply sophisticated object identification algorithms in order to locate targets of interest in images such as mines. Despite progress in this field, modern sonar automatic target recognition (ATR) approaches lack robustness to the amount of noise one would expect in real-world scenarios ...
John McKay 0002   +3 more
openaire   +2 more sources

Real-Time, On-Site, Machine Learning Identification Methodology of Intrinsic Human Cancers Based on Infra-Red Spectral Analysis – Clinical Results [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2020
In this work we present a real-time (RT), on-site, machine-learning based methodology for identifying intrinsic human cancers. The presented approach is reliable, effective, cost-effective and non-invasive and based on the Fourier transform infrared ...
Yaniv Cohen   +3 more
doaj  

How Does Exposure to Changing Opinions or Reaffirmation Opinions Influence the Thoughts of Observers and Their Trust in Robot Discussions?

open access: yesApplied Sciences, 2022
This study investigated how exposure to changing or reaffirmation opinions in robot conversations influences the impressions of observers and their trust in media.
Hiroki Itahara   +4 more
doaj   +1 more source

Historical Documents and Automatic Text Recognition: Introduction [PDF]

open access: yesJournal of Data Mining and Digital Humanities
With this special issue of the Journal of Data Mining and Digital Humanities (JDMDH), we bringtogether in one single volume several experiments, projects and reflections related to automatic textrecognition applied to historical documents.
Ariane Pinche, Peter Stokes
doaj   +1 more source

Carcinogenesis in Ulcerative Colitis: Is Surveillance Worthwhile?

open access: yesCanadian Journal of Gastroenterology, 1990
Observations that dysplastic epithelium predicts neoplastic change in the coli tic bowel have led to the adoption of surveillance policies in ulcerative colitis patients, usually involving colonoscopy irrespective of symptomatology.
ATR Axon
doaj   +1 more source

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