Results 11 to 20 of about 159,436 (257)
A direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling. [PDF]
TopBP1-like proteins, which include Xenopus laevis Xmus101, are required for DNA replication and have been linked to replication checkpoint control. A direct role for TopBP1/Mus101 in checkpoint control has been difficult to prove, however, because of ...
Lindsay, Howard D. +5 more
core +5 more sources
SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA-PKcs/CHK1 replicative checkpoint to inhibit cell growth in non-small cell lung cancer. [PDF]
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Shreim A +17 more
europepmc +2 more sources
Code that was used for the bioinformatics analysis reported in Szydzik J et al. ATR inhibition enables complete tumour regression in ALK-driven NB mouse models, Nature Communications ...
JimmyVdEynden
core +1 more source
Real-Time, On-Site, Machine Learning Identification Methodology of Intrinsic Human Cancers Based on Infra-Red Spectral Analysis – Clinical Results [PDF]
In this work we present a real-time (RT), on-site, machine-learning based methodology for identifying intrinsic human cancers. The presented approach is reliable, effective, cost-effective and non-invasive and based on the Fourier transform infrared ...
Yaniv Cohen +3 more
doaj
This study investigated how exposure to changing or reaffirmation opinions in robot conversations influences the impressions of observers and their trust in media.
Hiroki Itahara +4 more
doaj +1 more source
Carcinogenesis in Ulcerative Colitis: Is Surveillance Worthwhile?
Observations that dysplastic epithelium predicts neoplastic change in the coli tic bowel have led to the adoption of surveillance policies in ulcerative colitis patients, usually involving colonoscopy irrespective of symptomatology.
ATR Axon
doaj +1 more source
Historical Documents and Automatic Text Recognition: Introduction [PDF]
With this special issue of the Journal of Data Mining and Digital Humanities (JDMDH), we bringtogether in one single volume several experiments, projects and reflections related to automatic textrecognition applied to historical documents.
Ariane Pinche, Peter Stokes
doaj +1 more source
Chronic hepatitis B virus infection (CHB) caused by the hepatitis B virus (HBV) is one of the most common viral infections in the world. Reactivation of HBV infection is a life-threatening condition observed in patients with CHB receiving chemotherapy or
Anastasiya Kostyusheva +10 more
doaj +1 more source
Scattering characteristics of polygon plate
Polygon plates are basic structures of complex targets and exist in a variety of scenes. Therefore, the study of scattering characteristics about polygon plates is critical to auto target recognition (ATR).
Zhiming Xu +4 more
doaj +1 more source
ATR-FTIR data of buccal cells - OPUS
ATR-FTIR data from buccal cell ...
Maria Paraskevaidi (14586953)
core +1 more source

