Structural and strategic landscape of PIKK protein family and their inhibitors: an overview
Frontiers in Bioscience-Landmark, 2020 Phosphatidylinositol-3 kinase-related kinases (PIKKs) is a class of six unique serine/threonine kinases that are characterized as high molecular mass colossal proteins present in multicellular organisms.
Deekshi Angira +2 more
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Applied Sciences, 2022 This study investigated how exposure to changing or reaffirmation opinions in robot conversations influences the impressions of observers and their trust in media.
Hiroki Itahara +4 more
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BrainLiner: A Neuroinformatics Platform for Sharing Time-Aligned Brain-Behavior Data
Frontiers in Neuroinformatics, 2016 Data-driven neuroscience aims to find statistical relationships between brain activity and task behavior from large-scale datasets. To facilitate high-throughput data processing and modeling, we created BrainLiner as a web platform for sharing time ...
Makoto eTakemiya +4 more
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Claspin and the Activated Form of ATR-ATRIP Collaborate in the Activation of Chk1 [PDF]
, 2004 Claspin is necessary for the ATR-dependent activation of Chk1 in Xenopus egg extracts containing incompletely replicated DNA. ATR possesses a regulatory partner called ATRIP. We have studied the respective roles of ATR-ATRIP and Claspin in the activation
Dunphy, William G. +2 more
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Genotoxic stress signalling as a driver of macrophage diversity
Cell Stress, 2022 Tissue macrophages arise from yolk sac, fetal liver and hemato-poietic progenitors and adopt diverse transcriptional programs and phenotypes, instructed by their microenvironment.
Ana Kasapi, Antigoni Triantafyllopoulou
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The Rad9-Hus1-Rad1 Checkpoint Clamp Regulates Interaction of TopBP1 with ATR [PDF]
, 2007 TopBP1 serves as an activator of the ATR-ATRIP complex in response to the presence of incompletely replicated or damaged DNA. This process involves binding of ATR to the ATR-activating domain of TopBP1, which is located between BRCT domains VI and VII ...
Dunphy, William G. +2 more
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A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome. [PDF]
, 2018 The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis.
Bacova, Maria +11 more
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Real-Time, On-Site, Machine Learning Identification Methodology of Intrinsic Human Cancers Based on Infra-Red Spectral Analysis – Clinical Results [PDF]
Journal of Systemics, Cybernetics and Informatics, 2020 In this work we present a real-time (RT), on-site, machine-learning based methodology for identifying intrinsic human cancers. The presented approach is reliable, effective, cost-effective and non-invasive and based on the Fourier transform infrared ...
Yaniv Cohen +3 more
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Evidence for Respiratory Neuromodulator Interdependence after Cholinergic Disruption in the Ventral Respiratory Column [PDF]
, 2015 Reverse dialysis of the muscarinic receptor antagonist, atropine (ATR, 50 mM), into the pre-Bötzinger Complex region of the ventral respiratory column (VRC) of awake and sleeping goats increases breathing frequency and serotonin (5-HT), substance P (SP),
Forster, Hubert +6 more
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Turkish Journal of Agriculture: Food Science and Technology, 2023 Microorganisms have various stress response systems to maintain their viability when exposed to different stress conditions. In this study, Lactobacillus acidophilus ATCC 4356 and Bifidobacterium bifidum ATCC 11863 strains, used in probiotic yoghurt ...
Şehriban Oğuz +3 more
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