Results 31 to 40 of about 352,507 (310)
Carcinogenesis in Ulcerative Colitis: Is Surveillance Worthwhile?
Canadian Journal of Gastroenterology, 1990 Observations that dysplastic epithelium predicts neoplastic change in the coli tic bowel have led to the adoption of surveillance policies in ulcerative colitis patients, usually involving colonoscopy irrespective of symptomatology.
ATR Axon
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Historical Documents and Automatic Text Recognition: Introduction [PDF]
Journal of Data Mining and Digital HumanitiesWith this special issue of the Journal of Data Mining and Digital Humanities (JDMDH), we bringtogether in one single volume several experiments, projects and reflections related to automatic textrecognition applied to historical documents.
Ariane Pinche, Peter Stokes
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Viruses, 2019 Chronic hepatitis B virus infection (CHB) caused by the hepatitis B virus (HBV) is one of the most common viral infections in the world. Reactivation of HBV infection is a life-threatening condition observed in patients with CHB receiving chemotherapy or
Anastasiya Kostyusheva +10 more
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Scattering characteristics of polygon plate
The Journal of Engineering, 2019 Polygon plates are basic structures of complex targets and exist in a variety of scenes. Therefore, the study of scattering characteristics about polygon plates is critical to auto target recognition (ATR).
Zhiming Xu +4 more
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Cell Cycle, 2006 ATR is a critical upstream regulator of checkpoint responses to incompletely replicated and damaged DNA. However, it had not been understood how the kinase activity of ATR is switched on during checkpoint responses. TopBP1 and its homologs are necessary for both DNA replication and checkpoint control.
Akiko, Kumagai, William G, Dunphy
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Hybrid Structure-Adaptive RBF-ELM Network Classifier
IEEE Access, 2017 In this paper, a hybrid structure-adaptive radial basis function-extreme learning machine (HSARBF-ELM) network classifier is presented. HSARBF-ELM consists of a structure-adaptive radial basis function (SARBF) network and an extreme learning machine (ELM)
Hui Wen +3 more
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Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling [PDF]
, 2007 Large brain size is one of the defining characteristics of modern humans. Seckel syndrome (MIM 210600), a disorder of markedly reduced brain and body size, is associated with defective ATR-dependent DNA damage signaling.
A Kramer +42 more
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Cell, 2006 The nuclear protein kinase ATR is a key regulator of genome integrity that functions at checkpoints for damaged or incompletely replicated DNA. In this issue of Cell, Kumagai et al. (2006) shed light on the molecular mechanism that controls ATR. They report that a physical interaction between ATR and a distinct domain of TopBP1 greatly enhances ATR ...
Bartek, Jiri, Mailand, Niels
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Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA [PDF]
Nature Communications, 2018 AbstractATR kinase is activated by RPA-coated single-stranded DNA (ssDNA) to orchestrate DNA damage responses. Here we show that ATR inhibition differs from ATR loss. Mouse model expressing kinase-dead ATR (Atr+/KD), but not loss of ATR (Atr+/−), displays ssDNA-dependent defects at the non-homologous region of X-Y chromosomes during male meiosis ...
Demis Menolfi +8 more
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Frontiers in Computational Neuroscience, 2015 The inverse problem for estimating model parameters from brain spike data is an ill-posed problem because of a huge mismatch in the system complexity between the model and the brain as well as its non-stationary dynamics, and needs a stochastic approach ...
Huu eHoang +7 more
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