Results 141 to 150 of about 33,070 (201)
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Background Sarcopenia is a progressive, age‐related condition characterized by a decline in skeletal muscle mass, strength and performance. Diagnosis remains challenging because current consensus criteria are difficult to scale and existing biomarkers lack accuracy.
Dongqin Xu +10 more
wiley +1 more source
Epstein‐Barr Virus Infection at Single‐Cell Resolution
Journal of Medical Virology, Volume 98, Issue 2, February 2026.ABSTRACT Epstein‐Barr virus (EBV) infection has been studied at single‐cell resolution for six decades and counting. Such investigations can reveal virus‐host interactions and their dependence on viral strain, cellular niche, infection program, immune response regulation, and time.
Elliott D. SoRelle
wiley +1 more source
Deceptive beauty of non‐natural structures
Protein Science, Volume 35, Issue 2, February 2026.Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich +1 more
wiley +1 more source
Editorial: Atypical Functions of Leukocyte Chemoattractant Receptors
Frontiers in Immunology, 2020 José Luis Rodríguez-Fernández +3 more
doaj +1 more source
Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.Bacterial contaminants in occupational environments may elicit an immune response. This study investigated the immune‐modulatory potential of bacterial communities using in vitro cell‐based assays and revealed distinctive bacterial species as drivers of TLR2 and TLR4 activation. The presented approach studied the role of bacterial species as modulators
Elke Eriksen +2 more
wiley +1 more source
The biology of PKM2 in the metabolism and senescence in diabetic kidney disease
Journal of Diabetes Investigation, Volume 17, Issue 2, Page 197-204, February 2026.ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley +1 more source
Astrocyte Regulation of Spinal Circuit Function
Journal of Neurochemistry, Volume 170, Issue 2, February 2026.Spinal cord astrocytes exist as an additional component of the computational framework that governs both sensory perceptions and motor outputs (left). By integrating local synaptic activity together with signals that reflect whole‐body state (e.g., neuromodulators, immune signals, and vascular signals) into defined input states (Sn), astrocytes adapt ...
Mary Kaye Duff +2 more
wiley +1 more source
Receptor‐Dependent and ‐Independent Effects of Hemin on Platelet Plasma Membrane Disintegration
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Microhemorrhages lead to the release of erythrocytes, which are then degraded and lysed. These hemolyses result in the liberation of free iron‐containing hemin. Hemin induces platelet activation and ferroptosis. Inhibition of GPVI/CLEC‐2 receptor‐mediated ITAM‐signaling inhibits hemin‐induced platelet activation (low hemin concentrations). Deferoxamine,
Zoi Laspa +5 more
wiley +1 more source
The atypical chemokine receptor-2 fine-tunes the immune response in herpes stromal keratitis. [PDF]
Front Immunol, 2022 Yu T +5 more
europepmc +1 more source
The dimeric form of CXCL12 binds to atypical chemokine receptor 1. [PDF]
Sci Signal, 2021 Gutjahr JC +10 more
europepmc +1 more source