Results 151 to 160 of about 28,527 (253)

Integrated Proteomic and Metabolomic Profiling for Developing Novel Plasma‐Based Diagnostic Models of Sarcopenia

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Sarcopenia is a progressive, age‐related condition characterized by a decline in skeletal muscle mass, strength and performance. Diagnosis remains challenging because current consensus criteria are difficult to scale and existing biomarkers lack accuracy.
Dongqin Xu, Haoran Jin, Jinlin Yang, Zhiliang Zuo, Rui Ou, Fengjuan Hu, Lu Pu, Yuxing Dong, Meng Wu, Birong Dong, Hao Jiang   +10 more
wiley   +1 more source

Epstein‐Barr Virus Infection at Single‐Cell Resolution

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Epstein‐Barr virus (EBV) infection has been studied at single‐cell resolution for six decades and counting. Such investigations can reveal virus‐host interactions and their dependence on viral strain, cellular niche, infection program, immune response regulation, and time.
Elliott D. SoRelle
wiley   +1 more source

Deceptive beauty of non‐natural structures

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich, Eugenia V. Gurevich   +1 more
wiley   +1 more source

Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3)

, 2023
Sebastian Dekkers, Dehan Çömez, Noémi Karsai, Marta Arimont, Meritxell Canals, Birgit Caspar, Chris de Graaf, Laura E. Kilpatrick, Rob Leurs, Barrie Kellam, Stephen J. Hill, Stephen J. Briddon, Michael J. Stocks   +12 more
openalex   +1 more source

Bacterial Communities as Modulators of Innate Immune Signalling: An In Vitro Perspective on Toll‐Like Receptor Activation

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Bacterial contaminants in occupational environments may elicit an immune response. This study investigated the immune‐modulatory potential of bacterial communities using in vitro cell‐based assays and revealed distinctive bacterial species as drivers of TLR2 and TLR4 activation. The presented approach studied the role of bacterial species as modulators
Elke Eriksen, Pål Graff, Anani Komlavi Afanou   +2 more
wiley   +1 more source

Reactivity of human and porcine natural interferon-alpha producing cells to immunostimulatory DNA [PDF]

, 2003
The interferon-α (IFN-α) inducing capacity of various forms of immunostimulatory DNA and the identity of the IFN-α producing cells (IPC) were studied in human and porcine leukocytes.
Magnusson, Mattias
core  

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 197-204, February 2026.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

The atypical chemokine receptor 2 reduces T cell expansion and tertiary lymphoid tissue but does not limit autoimmune organ injury in lupus-prone B6lpr mice

Frontiers in Immunology
IntroductionThe atypical chemokine receptor 2 (ACKR2) is a chemokine scavenger receptor, which limits inflammation and organ damage in several experimental disease models including kidney diseases.
Wenkai Xia, Wenkai Xia, Nuru Eltrich, Volker Vielhauer   +3 more
doaj   +1 more source

Astrocyte Regulation of Spinal Circuit Function

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Spinal cord astrocytes exist as an additional component of the computational framework that governs both sensory perceptions and motor outputs (left). By integrating local synaptic activity together with signals that reflect whole‐body state (e.g., neuromodulators, immune signals, and vascular signals) into defined input states (Sn), astrocytes adapt ...
Mary Kaye Duff, Min Jun Li, Axel Nimmerjahn   +2 more
wiley   +1 more source

Data from Regulation of Breast Cancer Metastasis by Atypical Chemokine Receptors

, 2023
Xiaoyun Cheng, Mien‐Chie Hung
openalex   +2 more sources