Results 61 to 70 of about 25,762 (279)
Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005 [PDF]
, 2007 The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management
D. YOUNG +8 more
core +2 more sources
Haematologica, 2017 Paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome are diseases of excess activation of the alternative pathway of complement that are treated with eculizumab, a humanized monoclonal antibody against the terminal complement ...
Xuan Yuan +8 more
doaj +1 more source
Hemolytic uremic syndrome (HUS) – case report
Journal of Education, Health and Sport, 2020 Introduction Hemolytic uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia and acute renal failure. In 90% of children, HUS most often develops after an intestinal infection caused by verotoxin-producing E. coli. The remaining 10%
Aleksandra Borkowska +5 more
doaj +1 more source
Atypical hemolytic-uremic syndrome in children
Инновационная медицина Кубани, 2022 Background: Atypical hemolytic-uremic syndrome (aHUS) is a rare progressive form of systemic thrombotic microangiopathy (TMA), which develops due to uncontrolled activation of the alternative pathway of the complement system and is characterized by a ...
A. V. Burlutskaya +3 more
doaj +1 more source
Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]
, 2010 Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Catlow, Jamie +4 more
core +1 more source
Two patients with history of STEC-HUS, posttransplant recurrence and complement gene mutations [PDF]
, 2013 Hemolytic uremic syndrome (HUS) is a disease of microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. About 90% of cases are secondary to infections by Escherichia coli strains producing Shiga-like toxins (STEC-HUS), while 10% are ...
Alberti, M. +8 more
core +1 more source
Epidemiology of Atypical Hemolytic Uremic Syndrome: A Systematic Literature Review
Clinical Epidemiology, 2020 Atypical hemolytic uremic syndrome (aHUS) is a rare but severe disorder that frequently has a genetic component and results from the overactivation of the alternative complement pathway. As research moves toward improved diagnosis and therapy of aHUS, it
K. Yan +4 more
semanticscholar +1 more source
Journal of Medical Economics, 2022 Aims This study compared the aggregate duration of treatment administration of approved eculizumab and ravulizumab treatment regimens and resultant productivity implications for patients with atypical hemolytic uremic syndrome (aHUS) and their caregivers.
A. Levy +5 more
semanticscholar +1 more source
Genetics of Atypical Hemolytic Uremic Syndrome (aHUS) [PDF]
Seminars in Thrombosis and Hemostasis, 2014 Hemolytic uremic syndrome (HUS) is a rare, life-threatening disease characterized by thrombocytopenia, microangiopathic hemolytic anemia, and acute renal failure. The atypical form of HUS (aHUS), representing 5 to 10% of cases, lacks the association with infection by Shiga toxin producing Escherichia coli strains that characterizes the commonest ...
Rodriguez de Cordoba, Santiago +3 more
openaire +4 more sources
Factor H gene variants in Japanese: Its relation to atypical hemolytic uremic syndrome [PDF]
, 2011 Mutations and polymorphisms of factor H gene (FH1) are known to be closely involved in the developmentof atypical hemolytic uremic syndrome (aHUS). Several groups have identified disease risk mutations andpolymorphisms of FH1 for the development of aHUS,
Fujihara Noriko +10 more
core +1 more source