Results 141 to 150 of about 32,508 (252)

Building an Interleukin‐10‐Producing Identity: How B Cells Acquire Interleukin‐10 Competence and How Plasma Cell Differentiation Consolidates This Program

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Interleukin (IL)‐10‐producing B cells represent an archetype for the regulatory functions of B cells. Here, we review the cell‐surface receptors and transcriptional regulators that control IL‐10 expression in B cells and enable their regulatory function in vivo.
Bui Thi Cuc, Yanli Tong, Zhiguo Wu, Daniel Alvarez‐Simon, Simon Fillatreau   +4 more
wiley   +1 more source

Advances in the treatment of systemic lupus erythematosus: Biologicals, small‐molecular agents, and cell‐depleting therapies coming to the clinic

Journal of Internal Medicine, Volume 300, Issue 4, Page 461-479, October 2026.
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

The cascade to pathogenicity in autoantibody-mediated CNS diseases. [PDF]

Brain
Montini F, Wing E, Herman M, Pittock SJ, Lopez Chiriboga S, Flanagan EP, Irani SR.   +6 more
europepmc   +1 more source

Differentiating naturally occurring and disease associated autoantibodies in MPO-ANCA vasculitis through immunogenomic and epitope comparisons. [PDF]

Front Med (Lausanne)
Chen DP, Moon YH, Peck BA, Taylor JJ, Gomez-Martinez I, Woodcock MG, Vincent BG, Falk RJ, Poulton JS, Bunch DO.   +9 more
europepmc   +1 more source

Generation of Regulatory T Cells Against Islet Neoantigen. [PDF]

Eur J Immunol
Den Hollander NHM, Gootjes C, Staal MG, Joosten AM, Nikolic T, Roep BO, Jansen DTSL.   +6 more
europepmc   +1 more source

Autoantigen identification in antinuclear antibody-positive usual interstitial pneumonia without known autoantibody through immunoprecipitation-mass spectrometry. [PDF]

ERJ Open Res
Vulsteke JB, De Langhe E, De Sadeleer L, De Crem N, Yserbyt J, Dubbeldam A, Wuyts WA, Bossuyt X.   +7 more
europepmc   +1 more source

Immunopathogenesis of Immune Checkpoint Inhibitor-Induced Myositis, Myocarditis and Myasthenia Gravis Overlap Syndrome: A Mechanistic Synthesis of a Mitochondrial Autoantigen Hypothesis. [PDF]

Cureus
Ismail U.
europepmc   +1 more source

Artery tertiary lymphoid organs encode a pathogenic high-affinity autoantibody-autoantigen pair in atherosclerosis. [PDF]

Nat Cardiovasc Res
Zhang C, Zhang X, Ran Y, Wang Z, Li L, Wang S, Zheng J, Zhang Y, Sun T, Li Y, Lu S, Hong M, Ma Z, Steffens S, Hristov M, Blanchet X, Zhu J, Dou X, Deng X, Dornmair K, Hu D, Lahiri S, Imhof A, Sachs N, Maegdefessel L, Xiao J, Zhang J, Wang Y, Hong H, Habenicht L, Weng X, Ge J, Weber C, Santovito D, Bashford-Rogers R, Mohanta SK, Ley K, Habenicht AJR, Yin C.   +38 more
europepmc   +1 more source