Results 211 to 220 of about 32,508 (252)

Golgi Autoantibodies and Autoantigens

Journal of Autoimmunity, 1994
Autoantibodies directed against cellular constituents rarely react with antigens localized in the Golgi apparatus and little information is available regarding these particular antibodies. Although thousands of samples have been examined for autoantibodies in our laboratory on a routine basis, only three human sera with anti-Golgi antibodies could be ...
G, Renier, M C, Rousselet, F, Carrere, A, Croue, C, André, F, Oksman, A, Chevailler, D, Hurez   +7 more
openaire   +2 more sources

Autoantigens in an immunological network

Medical Hypotheses, 1983
An autoantigen network, consisting of all non-lymphoid cells and a subset of peripherally located autoregulatory lymphocytes, is proposed. By equilibrating a web of idiotypic stimulation (helper activity) and antiidiotypic inhibition (suppressor activity) directed at each tissue differentiation antigen, this network quantitatively limits autoantigen ...
F T, Vertosick, R H, Kelly
openaire   +2 more sources

Factors Governing B Cell Recognition of Autoantigen and Function in Type 1 Diabetes

Antibodies
Islet autoantibodies predict type 1 diabetes (T1D) but can be transient in murine and human T1D and are not thought to be directly pathogenic. Rather, these autoantibodies signal B cell activity as antigen-presenting cells (APCs) that present islet ...
Rachel A. Henry Bonami, Lindsay Bass
exaly   +2 more sources

Tolerance in the Absence of Autoantigen

Endocrine‚ Metabolic & Immune Disorders-Drug Targets, 2007
Regulatory T (T(reg)) cells show promise for treating autoimmune diseases, but their induction to elevated potency has been problematic when the most optimally derived cells are from diseased animals. To circumvent reliance on auto-antigen reactive T(reg) cells, stimulation to vaccine antigens (Ags) may offer a viable alternative while maintaining ...
D W, Pascual, J, Ochoa-Repáraz, A, Rynda, X, Yang   +3 more
openaire   +2 more sources

Hepatic and biliary Autoantigens

Immunological Investigations, 1989
Chronic active hepatitis (CAH) and primary biliary cirrhosis (PBC) are two enigmatic liver diseases in which autoimmunity is implicated. Provisional criteria to separate the autoimmune type of CAH (A-CAH) from others are specified. Western immunoblotting using disease sera and antibody screening of a rat liver gene expression library were used to ...
openaire   +2 more sources

Autoantigens and Sjögren Syndrome

Cornea, 2002
To review recent experimental evidence on the involvement of autoantigens and autoantibodies in the pathogenesis of organ-specific autoimmunity in Sjögren syndrome (SS).Among candidate autoantigens in SS, we investigated the role of alpha-fodrin in the lacrimal gland using a mouse model and a lacrimal gland cell line established in p53 knockout mice ...
openaire   +2 more sources

New strategy for MS treatment with autoantigen-modified liposomes and their therapeutic effect

Journal of Controlled Release, 2021
Yasuhiro Magata, Naoto Oku, Yudai Narita
exaly  

NATIVE AUTOANTIGENS VERSUS RECOMBINANT AUTOANTIGENS

2007
PATRICK S.C. LEUNG, M. ERIC GERSHWIN
openaire   +1 more source

Autoantigene

2003
Günter Steiner, Karsten Conrad
openaire   +1 more source

Autoantigens

2011
  +4 more sources