Results 81 to 90 of about 49,748 (241)

Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation [PDF]

open access: gold, 2022
Theresa Kissel   +23 more
openalex   +1 more source

Antibody Reactivity of B Cells in Lupus Patients with Increased Disease Activity and ARID3a Expression

open access: yesAntibodies, 2015
Earlier studies showed that the DNA-binding protein, Bright/ARID3a bound to a subset of human and mouse immunoglobulin heavy chain promoters where it enhanced expression.
Julie M. Ward   +3 more
doaj   +1 more source

Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis [PDF]

open access: yes, 2013
Rheumatoid arthritis (RA) is a systemic inflammatory disease resulting from an autoimmune response to self-antigens, leading to infl ammation of synovial tissue of joints and subsequent cartilage and bone erosion. Current disease-modifying anti-rheumatic
Thomas, Ranjeny
core   +2 more sources

Cross-reactive immune responses between enteroviruses and islet cell autoantigens [PDF]

open access: yes, 2002
Ohjaaja Merja Roivainen/MIBO ...
Härkönen, Taina
core  

Rat models of autoimmune uveitis [PDF]

open access: yes, 2008
Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Diedrichs-Moehring, Maria   +2 more
core   +1 more source

Insulin gene polymorphisms in type I diabetes, Addison's disease and the polyglandular autoimmune syndrome type II [PDF]

open access: yes, 2008
Background: Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from ß-cell ...
Badenhoop, Klaus   +9 more
core   +2 more sources

Macrophage Scavenger Receptor 1 (Msr1, SR-A) Influences B Cell Autoimmunity by Regulating Soluble Autoantigen Concentration [PDF]

open access: bronze, 2013
Stefanie Haasken   +7 more
openalex   +1 more source

Triggers of Autoimmunity: The Role of Bacterial Infections in the Extracellular Exposure of Lupus Nuclear Autoantigens

open access: yesFrontiers in Immunology, 2019
Infections are considered important environmental triggers of autoimmunity and can contribute to autoimmune disease onset and severity. Nucleic acids and the complexes that they form with proteins—including chromatin and ribonucleoproteins—are the main ...
Connie C. Qiu   +2 more
doaj   +1 more source

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